Pentoxifylline as a potential adjuvant therapy for COVID-19: impeding the burden of the cytokine storm

W Feret, M Nalewajska, Ł Wojczyński… - Journal of Clinical …, 2021 - mdpi.com
… Except for tocilizumab, a monoclonal antibody against IL-6 receptors that has been proven …
other therapeutic approaches have thus far been introduced for countering the cytokine storm

The meteorology of cytokine storms, and the clinical usefulness of this knowledge

IA Clark, B Vissel - Seminars in immunopathology, 2017 - Springer
… , as well as focus on the therapeutic possibilities of this knowledge, which is a main theme
of this text. We also extend the concept of a cytokine storm into the chronic neurodegenerative …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
… The suggested prognostic scale (including the NEWS score dynamics; serum IL-6 greater
than 23 … at a high risk for cytokine storm, requiring an early onset of anti-inflammatory therapy. …

Taming the storm in the heart: exploring different therapeutic choices against myocardial inflammation in COVID-19

A Choudhury, S Mukherjee - Recent Advances in Anti-Infective …, 2021 - ingentaconnect.com
… ‘cytokine storm’. As a result, TLRs are now considered as the therapeutic targets to develop
efficacious therapeutics… -19 patients and the therapeutic promises of TLR-targeted therapies. …

Role of PKM2-mediated immunometabolic reprogramming on development of cytokine storm

Z Liu, Y Le, H Chen, J Zhu, D Lu - Frontiers in immunology, 2021 - frontiersin.org
therapeutic target for the treatment of cytokine storm-… cytokine storm. The findings of the
study will provide a basis for the development of novel therapies for managing the cytokine storm

The therapeutic effect and mechanism of parthenolide in skeletal disease, cancers, and cytokine storm

S Zhu, P Sun, S Bennett, O Charlesworth… - Frontiers in …, 2023 - frontiersin.org
… In this review, we summarise the recent research progress of medicinal PTL, including the
therapeutic effects on skeletal diseases, cancers, and inflammation-induced cytokine storm. …

Repurposing of drugs targeting the cytokine storm induced by SARS‐CoV‐2

WH Ng, PCH Tang, S Mahalingam… - British Journal of …, 2023 - Wiley Online Library
… potential as a new therapy for SARS-CoV-2-induced ARDS, in which the cytokine storm plays
an immunopathological role. This minireview includes anti-cytokine drugs tested in COVID-…

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or
cytokine release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
… )-2, IL-4, IL-6, IL-8, IL-1β, and so forth. Characterized as “cytokine storm” that may have
occurred due to an imbalanced immune system. The cytokine storm is also considered to be one …

[PDF][PDF] The cytokine storm in COVID-19 patients amenable to stem cell treatment: A perspective

K Sidhu - Stem Cells Regen Med, 2020 - scivisionpub.com
… a terrible cytokine storm in the lung, with influx of IL-2, IL-6, IL-7, … this cytokine storm, one
or two immune factors alone may not work. Therefore, any mechanism to combat cytokine storm