… , early treatment, and the development of therapies that target specific pathophysiological
components of the heterogeneous mechanisms of MS, which could alleviate the symptoms …

Endothelial dysfunction has been implicated as a key factor in the development of a wide
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …

… mechanisms function at many levels to orchestrate the regulation of apoptosis, a multitude of
opportunities for … Several of the molecular mechanisms by which cancer cells are protected …

Dietary selenium (]Se), mainly through its incorporation into selenoproteins, plays an
important role in inflammation and immunity. Adequate levels of Se are important for initiating …

Simple Summary Metastasis, the process by which cancer cells escape primary tumor site
and colonize distant organs, is responsible for most cancer-related deaths. The tumor …

An imbalance in reducing and oxidizing (redox) systems favoring a more oxidative environment
is present in asthma and linked to the pathophysiology of the defining symptoms and …

Given their essential function in aerobic metabolism, mitochondria are intuitively of interest
in regard to the pathophysiology of diabetes. Qualitative, quantitative, and functional …

… Therapies targeting the redox environment show promise for these cases. This review
highlights the molecular mechanisms that control the redox milieu of leukemia cells. In particular, …

… The molecular mechanisms leading to AD have been shown to include dysfunctions in
several biological processes, including oxidative stress, inflammatory responses and altered …

… therapeutic strategies based on iron deprivation have been developed in cancer therapy. …
of genetic association and molecular mechanisms between iron and tumorigenesis has …