[HTML][HTML] Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future

R Shetty, A Ghosh, SG Honavar… - Indian journal of …, 2020 - journals.lww.com
… to its mode of action against the SARS coronavirus family.[ 95 ] The … therapeutic options
currently available to us in the face of this incredible threat to human life. Most of the therapeutic

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
therapies available to combat COVID-19. We focus on currently recommended therapeutic
… 19 that either show no or only limited therapeutic activity. The results of recent studies report …

[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
SARS-CoV-2 proteins can … of SARS-CoV-2 from the whole viral particle to the individual
viral proteins and discuss their functions as well as their potential as targets for therapeutic

[HTML][HTML] Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

C Wu, Y Liu, Y Yang, P Zhang, W Zhong… - … Pharmaceutica Sinica B, 2020 - Elsevier
SARS-CoV-2 and SARS-CoV, the structure and function prediction of SARS-CoV-2
genome … protein were mainly based on those researches on homology protein in SARS-CoV. …

Structural impact of mutation D614G in SARS-CoV-2 spike protein: enhanced infectivity and therapeutic opportunity

A Fernández - ACS medicinal chemistry letters, 2020 - ACS Publications
… The results raise the therapeutic possibility of immunologically targeting the epitope … means
of reducing the infection efficacy of SARS-CoV-2. This therapeutic modality would not a-priori …

SARS-CoV-2 antiviral therapy

K Tao, PL Tzou, J Nouhin, H Bonilla… - Clinical microbiology …, 2021 - Am Soc Microbiol
… In conclusion, the main therapeutic advance during the pandemic has been the development
of highly potent neutralizing MAbs for the prevention and treatment of SARS-CoV-2. The …

Potential therapeutic targets and promising drugs for combating SARSCoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
SARS-CoV-2 (Cabrini, Landoni, & Zangrillo, 2020). Several studies demonstrated ACE2 as
an important therapeutic target of SARS-CoV-… the potential therapeutic targets involved in the …

Vaccine development and therapeutic design for 2019‐nCoV/SARSCoV‐2: Challenges and chances

M Ghaebi, A Osali, H Valizadeh… - Journal of cellular …, 2020 - Wiley Online Library
… -2 outbreak, it is vital to find new targets for novel therapeutic anti-SARS-CoV-2 approach. …
nCoV is genetically closely related to SARS coronavirus (about 79% identity) and MERS-CoV

[HTML][HTML] Repurposing therapeutics for potential treatment of SARS-CoV-2: a review

J Santos, S Brierley, MJ Gandhi, MA Cohen… - Viruses, 2020 - mdpi.com
SARS-CoV or MERS-CoV to strategically identify therapeutictherapies with evidence for
benefit in SARS-CoV and MERS-CoV infections are more likely to benefit patients with SARS

Therapeutic approaches for SARS-CoV-2 infection

A Gupta, A Pradhan, VK Maurya, S Kumar, A Theengh… - Methods, 2021 - Elsevier
… In this article, we summarize all the therapeutic antiviral … therapy, various adjunct therapies,
and phage technology to unravel insightful mechanistic pathways of targeting SARS-CoV-2 …