COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
cytokine storm focuses primarily on support and symptomatic treatment of inflammation,
cytokine storm … Recently, a number of specific anti-cytokine approaches have proven effective in …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
The outbreak of new coronavirus disease-20119 or COVID-19 infection has become a
global health emergency at the beginning of this year. Currently, no specific vaccines and …

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine stormstherapeutic

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… , do trigger life-threatening “cytokine storms” in the host which can … cytokine storms which
may prove useful in the clinic in the future and compare them to more traditional therapeutic

[PDF][PDF] Therapeutic potential of N-acetyl cysteine (NAC) in preventing cytokine storm in COVID-19: review of current evidence.

RR Mohanty, BM Padhy, S Das… - European Review for …, 2021 - europeanreview.org
… the use of NAC to review two key objectives, ie,: Therapeutic potential of NAC in decreasing
the immune activation and cytokine storm. Efficacy of NAC in management of COVID-19. We …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… that release cytokines (notably IL-1, IL-6 and TNF) and … (cytokine storm) and tissue damage.
Some drugs have been studied as therapeutic targets (block to viral entry or to cytokine storm

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

Critical roles of cytokine storm and bacterial infection in patients with COVID-19: Therapeutic potential of mesenchymal stem cells

B Arjmand, S Alavi-Moghadam, M Sarvari… - …, 2023 - Springer
… However, occasionally, exaggerated immune system inflammation and an excessive synthesis
of cytokines, known as a "cytokine storm," can deteriorate the patient's clinical condition. …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… the involvement of a cytokine storm [2]. Cytokine storm represents an exaggerated immune
… of pro-inflammatory cytokines and chemokines such as IFN-γ, TNF-α, IL-6, IL-1β, IL-18, …