… SARS-CoV-2 mediated cytokinestorm is associated with the mortality and morbidity of COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …
… that release cytokines (notably IL-1, IL-6 and TNF) and … (cytokinestorm) and tissue damage. Some drugs have been studied as therapeutic targets (block to viral entry or to cytokinestorm…
X Wang, Z He, X Zhao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
… Immunoregulatory therapies target the cytokinestorms induced by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes COVID‑19, and include …
A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… prominent cytokine … cytokine levels while discussing cytokine sources and biological functions. Finally, we discuss in brief potential therapies attempting to modulate the cytokinestorm. …
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - … and targeted therapy, 2021 - nature.com
… cytokines are produced during the crosstalk between epithelial cells and immune cells in COVID-19, which has linked the cytokinestorm … In addition, the challenges and prospects in the …
… have tried to implement therapies to mitigate the cytokinestorm in the treatment of COVID… cytokinestorms, analyzing its role in COVID-19 and providing a critical analysis of the therapies …
L Pearce, SM Davidson, DM Yellon - … Opinion on Therapeutic …, 2020 - Taylor & Francis
… Over-activity of chemotaxis triggers a macrophage activation syndrome (MAS) resulting in the release of pro-inflammatory cytokines. IL-6 and TNF- α are at the forefront of hyper-…
… excessive amount of cytokine serum level (cytokinestorm) has … Thus, the management of the cytokinestorm could be the … prospective treatment strategies for cytokinestorm in COVID-19…
T Amin, A Hossain, FB Zahed - … and Experimental Therapeutics, 2022 - researchgate.net
… the major threat this cytokinestorm-induced … the therapeutic interventions currently available to treat sepsis to get an overview. We would also focus on the association of cytokinestorm …