Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
cytokines and the induction of inflammatory cell death. These processes can contribute to
cytokine storm, … framework for innate immunity driving cytokine storm and organ damage in …

Is there a role for blood purification therapies targeting cytokine storm syndrome in critically severe COVID-19 patients?

G Chen, Y Zhou, J Ma, P Xia, Y Qin, X Li - Renal failure, 2020 - Taylor & Francis
… Their potential in removing inflammatory factors and other toxins prospects for the treatment
… Further cascade generating more cytokines is called secondary cytokine storms [Citation28]. …

IL-33 and the cytokine storm in COVID-19: from a potential immunological relationship towards precision medicine

F Furci, G Murdaca, A Allegra, L Gammeri… - International Journal of …, 2022 - mdpi.com
… The major event underlying the progression of the disease is a cytokine storm. The underlying
mechanisms responsible for this unconstrained inflammatory cytokine storm are not yet …

Nanomedicine approaches to reduce cytokine storms in severe infections

MA Rauf, M Nisar, H Abdelhady, N Gavande… - Drug Discovery …, 2022 - Elsevier
… We also detail the biology of cytokine storms in severe infections, the role of macrophage …
with macrophage-based nanomedicine therapy. Cytokine storms in infectious disease …

Treatment and prognosis of COVID‑19: Current scenario and prospects

X Li, T Li, H Wang - Experimental and therapeutic …, 2021 - spandidos-publications.com
therapy is risky and suitable for critically ill patients with low immunity and without a cytokine
storm… In conclusion, plasma therapy must be used with caution, and should be further studied…

[HTML][HTML] Therapeutic prospects of mesenchymal stem/stromal cells in COVID-19 associated pulmonary diseases: From bench to bedside

LS Zhang, Y Yu, H Yu, ZC Han - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
… novel therapeutic techniques in dealing with cytokine storm and … investigators have indicated
the therapeutic potentials of MSC-… in MSC-based therapeutics towards standardization and …

Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications

A Allegra, M Di Gioacchino, A Tonacci… - International journal of …, 2020 - mdpi.com
… of treatment of the cytokine storm is constituted by blood purification therapy. The capability
… Ulinastatin, a natural anti-inflammatory molecule, could have great prospects in the therapy

Feasibility of mesenchymal stem cell therapy for COVID-19: a mini review

J Li, X Wang, N Li, Y Jiang, H Huang… - … Gene Therapy, 2020 - ingentaconnect.com
… the clinical prospect and conclude the therapeutic effects and … cytokines and anti-inflammatory
cytokines or cytokine storms might … has become the key difficulty in therapeutic strategies. …

Potential Therapeutic Role of Mesenchymal-Derived Stem Cells as an Alternative Therapy to Combat COVID-19 through Cytokines Storm

TK Upadhyay, R Trivedi, F Khan, P Pandey… - Cells, 2022 - mdpi.com
… “cytokine storm”. As far as we know, there is no universally accepted definition for cytokine
storms or cytokine … A study found that an auto-amplifying cascade of cytokines triggered by an …

VISTA: a target to manage the innate cytokine storm

MA ElTanbouly, Y Zhao, E Schaafsma… - Frontiers in …, 2021 - frontiersin.org
… targeting of myeloid cells, and its potential therapeutic implications in the settings of
hyperinflammatory responses such as cytokine storms, driven by dysregulated immune responses to …