Anti-interferon-γ Therapy for Cytokine Storm Syndromes

F De Benedetti - Cytokine Storm Syndrome, 2019 - Springer
Cytokine storm syndromes (CSS) are classical examples of hyperinflammation. In
hyperinflammation, activation of the inflammatory response in an excessive manner (involving both …

COVID‐19 cooling: Nanostrategies targeting cytokine storm for controlling severe and critical symptoms

Y Zheng, Y Li, M Li, R Wang, Y Jiang… - Medicinal Research …, 2024 - Wiley Online Library
… ) or Cytokine Release Syndrome has reemerged in the … as an entry point and therapeutic
target to alleviate the severity … Here, we put forward the view of cytokine storm as a therapeutic

[HTML][HTML] The host immune responses to SARS-CoV-2 and therapeutic strategies in the treatment of COVID-19 cytokine storm

M Aliyu, SH Mozhgani, OK Gargari… - AIMS Allergy and …, 2021 - aimspress.com
… (IL)-6 forming the epicenter of cytokine storm (CS), thereby perpetuating signaling cascade
through JAK/… (immunosuppressive) therapy, cytokines, and cytokine receptor blockers for CS …

Critical roles of cytokine storm and bacterial infection in patients with COVID-19: Therapeutic potential of mesenchymal stem cells

B Arjmand, S Alavi-Moghadam, M Sarvari… - …, 2023 - Springer
… However, occasionally, exaggerated immune system inflammation and an excessive synthesis
of cytokines, known as a "cytokine storm," can deteriorate the patient's clinical condition. …

Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections

Y Wang, S Liu, L Li, L Li, X Zhou, M Wan, P Lou… - Journal of Controlled …, 2022 - Elsevier
… , therapeutics that can effectively resolve cytokine storms are urgently required in the clinic.
Some therapies … the mechanisms of cytokine storms are complicated, and many cytokines are …

Apoptotic cell therapy for cytokine storm associated with acute severe sepsis

K Netanel, A Avraham, R el-Amore, E Ran… - Cell Death and …, 2020 - search.proquest.com
… fested by both a cytokine/chemokine elevation (also known as ‘cytokine storm’) and immune
… Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients…

Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation

I Amigues, AH Pearlman, A Patel, P Reid… - Expert review of …, 2020 - Taylor & Francis
… In infection with two other highly pathogenic coronaviruses, SARS-CoV-1 and MERS-CoV,
this state of hyperinflammation has been likened to a cytokine storm syndrome (CSS). …

… pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine storm and inflammatory responses

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
… Hence, the present review focuses on several parameters, including the role of cytokine
storm in … strategies are also discussed to control the cytokine storm or hypercytokinemia. …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
… , featuring the cytokine storm’s pathological processes. Furthermore, we briefly reviewed
potential therapeutic agents that may modulate and alleviate cytokine storms. The literature …

[PDF][PDF] Cytokine storms caused by novel coronavirus 2019 and treatment for cardiac injury.

DM Zhang, SL Chen - European Review for Medical & …, 2020 - europeanreview.org
… This article reviews cytokine storms and conducts an … Based on the current literature, this
article defines a cytokine storm … This drug has very promising application prospects in clinical …