… for pathophysiological research; some cytokine therapies are already used as part of clinical
practice, ranging from early exploratory trials to well established therapies that have already …

… and bind to macrophage toll-like receptor-4 (TLR-4), leading to the activation of nuclear
factor-κB (NF-κB) and subsequently the production of proinflammatory cytokines such as TNF-α [ …

… for the rational design of checkpoint inhibitor-based combination therapies. Finally, we
propose possible treatment strategies that can be used to develop Treg-targeted therapies. …

… Our review focuses on the latest functional studies of pro-inflammatory cytokines (interleukins) …
perspective of cytokines (interleukins) and CXC chemokines-based therapeutic targets in …

… In general, MSC therapy for liver fibrosis is effective and … of MSC therapy for liver fibrosis
and the associated limitations, and we suggest some potential future applications of this therapy. …

… In this review, we discuss key therapeutic targets in the treatment of vascular inflammation,
placing basic research in a wider clinical perspective, as well as identifying outstanding …

… of proinflammatory cytokines such as interleukin 12, and enhanced T-cell activation (2, 4).
CD40 ligation of resting B cells also increases antigen-presenting function and, in addition, …

… a potential antiinflammatory cytokine. Numerous studies support … A therapeutic intervention
with drug inducing endogenous IL-… agents have shown promising prospects for remission of …

… and anti-inflammatory responses to CPB, but also on the therapeutic interventions, including
… lead to new prospects for interventions to dampen or reverse its effects. Such therapies may …

… Collectively, the results from several studies suggest that exogenous cannabinoids elicit a
shift from a Th1 proinflammatory cytokine expression profile to a Th2 anti-inflammatory profile, …