… Uric acid crystals, similar to all other particulates, activate the Nlrp3 inflammasome. … ,
though a role for the Nlrp3 inflammasome in mediating ischemia reperfusion injury has …

… critical roles in NLRP3 inflammasome activation. … NLRP3 inflammasome activation and
inhibitors that specifically and directly target NLRP3 to provide insights into therapeutic strategies …

… , K + efflux has been proposed as a common mechanism for NLRP3 inflammasome activation,
… pathway has gained considerable traction as a potential therapeutic strategy in Gram-…

… therapeutic strategies. To this end, there is a need to elucidate the regulatory mechanism of
NLRP3 inflammasome … in the regulation of NLRP3 inflammasome activation. Understanding …

… However, many aspects of the biology of NLRP3 inflammasome to stroke are still not well …
the NLRP3 inflammasomes increases, opportunities to develop new therapeutic strategies for …

… arthritis, while inhibition of NLRP3 function or expression can mediate … NLRP3 inflammasome
signaling has been pathophysiologically implicated, as well as NLRP3 inflammasome-…

… blockade to treat NAFLD/NASH, and optimization of the therapeutic strategy for NAFLD
remains a major challenge. Future research directions should focus on agents with good results …

… Thus, NLRP3 inflammasome is a key molecule involved in the pathogenesis of … NLRP3
inflammasome-based targeted therapies for CVDs and the clinical evaluation of these therapies …

… In conclusion, NLRP3 inflammasome is involved in the pathogenesis of RA. Targeting NLRP3
inflammasome with a small molecule inhibitor might be a novel therapeutic strategy for RA…

… system to develop new therapeutic strategies for the treatment of … The Nod-like receptor pyrin
containing 3 inflammasome (NLRP3… Recent data have demonstrated that NLRP3 activation …