NLRP3 inflammasome-driven pathways in depression: clinical and preclinical findings

FN Kaufmann, AP Costa, G Ghisleni, AP Diaz… - Brain, behavior, and …, 2017 - Elsevier
… system to develop new therapeutic strategies for the treatment of … The Nod-like receptor pyrin
containing 3 inflammasome (NLRP3… Recent data have demonstrated that NLRP3 activation …

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease

S Wang, YH Yuan, NH Chen, HB Wang - International …, 2019 - Elsevier
therapeutic strategies … of NLRP3 inflammasome/pyroptosis activation and their inflammatory
effects in PD. We also describe some NLRP3 inhibitors that may be potential PD therapeutic

[HTML][HTML] Role of the NLRP3 inflammasome in cancer

M Moossavi, N Parsamanesh, A Bahrami, SL Atkin… - Molecular cancer, 2018 - Springer
… Within HCC, the NLRP3 inflammasomeNLRP3 inflammasome pharmacologically may
repress proliferation and metastasis of HCC, suggesting that this could be a therapeutic strategy

[HTML][HTML] NLRP3 inflammasome: A promising therapeutic target for drug-induced toxicity

S Wei, W Ma, B Zhang, W Li - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
… focused on the role of NLRP3 inflammasome in drug-induced … NLRP3 inflammasome is
involved in the initiation and … Therapeutic strategies via inhibiting NLRP3 inflammasome for drug-…

Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review

Z Zhang, Y Zhang, M Zhang, C Yu, P Yang… - Critical Reviews in …, 2023 - Taylor & Francis
… that exert inhibiting effects on NLRP3 inflammasome from different protein sources and …
of FDBP on NLRP3 inflammasomes and its regulatory role in NLRP3 inflammasome-related …

[HTML][HTML] The NLRP3 inflammasome as a new target in respiratory disorders treatment

K Leszczyńska, D Jakubczyk, S Górska - Frontiers in Immunology, 2022 - frontiersin.org
therapeutic substances that can act as a specific antagonist of the NLRP3 inflammasome
and … In turn, this will allow developing the new therapeutic strategies for respiratory disorders. …

Role of microgliosis and NLRP3 inflammasome in Parkinson's disease pathogenesis and therapy

FM de Araújo, L Cuenca-Bermejo… - Cellular and Molecular …, 2022 - Springer
… , microglia and the inflammasome in the … inflammasome and microglial activation with
the pathogenesis, symptoms, progression and the possibilities for new therapeutic strategies

[HTML][HTML] Role of NLRP3 inflammasome in rheumatoid arthritis

H Yin, N Liu, KR Sigdel, L Duan - Frontiers in immunology, 2022 - frontiersin.org
… To provide a foundation for the development of therapeutic strategies, we will briefly
summarize the roles of NLRP3 inflammasome in RA and explore its potential clinical treatment. …

NLRP3 inflammasome in ischemic stroke: as possible therapeutic target

M Alishahi, M Farzaneh… - … Journal of Stroke, 2019 - journals.sagepub.com
… signaling may offer substantial promise in developing new therapeutic strategy for stroke. …
showed that inhibition of the NLRP3 inflammasome could be a potential therapeutic target for …

Sensing damage by the NLRP3 inflammasome

JC Leemans, SL Cassel… - Immunological reviews, 2011 - Wiley Online Library
… are important inflammatory stimuli in atherosclerosis development and reveal potentially
new therapeutic strategies to manage atherosclerosis and cardiovascular disease. …