[HTML][HTML] Confronting the threat of SARSCoV‑2: Realities, challenges and therapeutic strategies

R Wang, X Luo, F Liu, S Luo - … and Therapeutic …, 2021 - spandidos-publications.com
… Among the potential targets for SARSCoV‑2 therapy, the viral spike glycoprotein has been
… for SARSCoV‑2 infection are described and a progress report on the status of SARSCoV‑2 …

[HTML][HTML] Therapeutic strategies against COVID-19 and structural characterization of SARS-CoV-2: a review

GU Jeong, H Song, GY Yoon, D Kim… - Frontiers in …, 2020 - frontiersin.org
… specifically target SARS-CoV-2. This review discusses therapeutic strategies using promising
antiviral agents against SARS-CoV-2. In addition, structural characterization of potentially …

[HTML][HTML] Therapeutic strategies in the development of anti-viral drugs and vaccines against SARS-CoV-2 infection

JS Bhatti, GK Bhatti, N Khullar, AP Reddy… - Molecular …, 2020 - Springer
… Currently, we are looking for therapeutic strategies to counter the severe effects of the
SARS-CoV-2 infection. A preliminary clinical trial of chloroquine repurposing against SARS-CoV-2 …

[HTML][HTML] SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

CO Barnes, CA Jette, ME Abernathy, KMA Dam… - Nature, 2020 - nature.com
… of SARS-CoV-2 neutralization, we solved eight new structures of distinct COVID-19 human
neutralizing antibodies 5 in complex with the SARS-CoV-… into the potential for SARS-CoV-2 to …

Classical and alternative receptors for SARSCoV‐2 therapeutic strategy

SF Masre, NF Jufri, FW Ibrahim… - Reviews in medical …, 2021 - Wiley Online Library
… for effective therapeutic strategies to treat and prevent Covid-19 disease. As SARS-CoV-2
S … strategy to control the viral infection. Specifically, inhibition of the interaction between the …

Targeted therapy strategies against SARSCoV‐2 cell entry mechanisms: a systematic review of in vitro and in vivo studies

S Seyedpour, B Khodaei, AH Loghman… - Journal of Cellular …, 2021 - Wiley Online Library
… Targeted therapy strategies against SARS-CoV-2 cell entry mechanisms fall … strategies
targeting virus receptors on the host, strategies neutralizing SARS-CoV-2 spike protein, strategies

[HTML][HTML] The potential use of microRNAs as a therapeutic strategy for SARS-CoV-2 infection

J Hu, J Stojanović, S Yasamineh, P Yasamineh… - Archives of …, 2021 - Springer
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory … coronavirus
2 (SARS-CoV-2). To date, there is no effective therapeutic approach for treating SARS-CoV-2 …

Challenges for targeting SARS-CoV-2 proteases as a therapeutic strategy for COVID-19

K Steuten, H Kim, JC Widen, BM Babin… - ACS infectious …, 2021 - ACS Publications
… the use of an alternate spike protein processing pathway employed by SARS-CoV-2. …
therapeutic strategy for the treatment of COVID-19. However, because animal models of SARS-CoV

[HTML][HTML] Advances in the development of therapeutic strategies against COVID-19 and perspectives in the drug design for emerging SARS-CoV-2 variants

J Yin, C Li, C Ye, Z Ruan, Y Liang, Y Li, J Wu… - Computational and …, 2022 - Elsevier
… Currently, there is an urgent need to explore antiviral therapeutic targets and … therapeutic
strategies against COVID-19, namely drugs targeting the SARS-CoV-2 life cycle and SARS-CoV

[HTML][HTML] COVID-19: unmasking emerging SARS-CoV-2 variants, vaccines and therapeutic strategies

R Raman, KJ Patel, K Ranjan - Biomolecules, 2021 - mdpi.com
therapies for treating SARS-CoV-2 infection are in progress. In this review, we discuss the
effect of SARS-CoV-… , as well as leading therapeutic approaches and vaccines in development …