The transcription factor nuclear factor (NF)-κB is activated in certain cancers and in response
to chemotherapy and radiation. The transcriptional activation of genes associated with cell …

… of the role played by NF-κB in the adult CNS environment is still limited compared with other
systems. So far, the potential of a therapy targeting NF-κB to treat neurological diseases is …

… inflammatory diseases have effects on NF-κB activity. Although they do not specifically
target NF-κB inhibition, at least some of the effects are due to the inhibition of NF-κB activation. …

… of certain cancer therapy regimens. In order to appropriately move NF-κB inhibitors in the …
dictate the complexity of oncologic and therapeutic outcomes that are controlled by NF-κB. …

… κB (NF-κB) has been linked to downstream target genes involved in atherosclerosis. The
activation of the NF-κB family and its downstream target … , NF-κB is a potential therapeutic target …

… the nuclear factor–kappa B (NF-κB) activation pathway, which … attractive targets for developing
anti-inflammatory therapeutics… , NF-κB activation represents an attractive therapeutic target …

… for the NF-B pathway in MS pathogenesis and, thus, potential as a therapeutic target in MS.
… Targeting NF-B is an attractive therapeutic option for RR-MS, where inflammatory CNS infil…

… therapeutic outcomes that are controlled by NF-κB. In this review, the authors discuss the
rationale behind targeting NF-κB for cancer therapy… of some of the NF-κB inhibitors alone and in …

… Thal 3, IMiD3) therapies. These studies therefore confirm a central role for NF-κB in regulating
… milieu and further suggest the potential utility of novel therapeutics targeting NF-κB in MM. …

… the field with an emphasis on the role of NF-κB in chronic inflammation, and to discuss the
feasibility of therapeutic approaches based on the specific suppression of the NF-κB pathway. …