[HTML][HTML] Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control

P Durai, M Batool, M Shah, S Choi - Experimental & molecular medicine, 2015 - nature.com
… In 2012, a new human disease called Middle East respiratory syndrome (MERS), having
a high mortality rate, emerged in the Middle East. It was caused by a virus that was originally …

[HTML][HTML] Middle East respiratory syndrome and severe acute respiratory syndrome: current therapeutic options and potential targets for novel therapies

J Dyall, R Gross, J Kindrachuk, RF Johnson… - Drugs, 2017 - Springer
… Further, kinases are the most frequently targeted gene class in cancer therapy, second only
… as therapeutic targets [83, 84]. The therapeutic potential for host-targeted immunomodulatory …

A review of candidate therapies for Middle East respiratory syndrome from a molecular perspective

AA Rabaan, SH Alahmed… - Journal of Medical …, 2017 - microbiologyresearch.org
… Host cell proteases are therefore potential molecular therapeutic targets for MERS-CoV
prophylaxis and/or treatment (Fig. 2, Table 1). The TMPRSS2 inhibitor camostat, for example, …

Middle East respiratory syndrome: pathogenesis and therapeutic developments

H Choudhry, MA Bakhrebah, WH Abdulaal… - Future …, 2019 - Taylor & Francis
… The pathogenic agent of Middle East respiratory syndrome is … Following that case, another
patient from the Middle East … has spread in countries across Middle East and Europe [Citation7…

[HTML][HTML] Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma …

YH Wu, IJ Yeh, NN Phan, MC Yen, JH Hung… - Journal of Microbiology …, 2021 - Elsevier
Background Pathogenic coronaviruses include Middle East respiratory syndrome coronavirus
(MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and SARS-…

A review of treatment modalities for Middle East Respiratory Syndrome

Y Mo, D Fisher - Journal of Antimicrobial Chemotherapy, 2016 - academic.oup.com
… Most facilities and healthcare providers outside of the Middle East receiving patients have no
… The use of any therapeutics in MERS-CoV remains investigational. The therapeutic agents …

[HTML][HTML] Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): a review

S Mustafa, H Balkhy, MN Gabere - Journal of infection and public health, 2018 - Elsevier
… proteins can act as therapeutic targets, in which various therapeutic options have been
implemented and will be discussed in Sections "Various therapeutic agents against MERS-CoV …

A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

H Momattin, AY Al-Ali, JA Al-Tawfiq - Travel medicine and infectious …, 2019 - Elsevier
… most of the cases are linked to the Middle East [2]. So far there have … therapy and no
approved therapies for MERS-CoV infection by international or national societies. Few therapeutic

[HTML][HTML] Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy

S Uddin, M Ahmed, A Hussain, J Abubaker… - The American journal of …, 2011 - Elsevier
… of CRC in Middle Eastern populations and genes that could be targeted in cancer therapy,
we … gene on the clinicopathological outcome of Middle Eastern CRC, protein expression of …

[HTML][HTML] Deep targeted sequencing analysis of hot spot mutations in non-small cell lung cancer patients from the Middle Eastern population

P Khoueiry, G Fakhri, R Akel, M El Assaad… - Journal of Thoracic …, 2019 - ncbi.nlm.nih.gov
targeted therapy readily available for patients. Deep … Middle East using deep targeted
sequencing. In the present study, we characterized recurrent hot spot mutations in Middle Eastern