Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - … and targeted therapy, 2021 - nature.com
… factors are potential targets for antiviral therapy. Hence, in this study, the current therapeutic
strategies of COVID-19 have been classified into “target virus” and “target host” categories. …

Precision therapeutic targets for COVID-19

ZA Krumm, GM Lloyd, CP Francis, LH Nasif… - Virology journal, 2021 - Springer
coronavirus 2 (SARS-CoV-2) emerged as a novel pathogen that causes coronavirus disease
2019 (COVID-19). … and clinical drugs that precisely target three different, essential steps of …

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
… (234) NSC61610 (Figure 20) induces lanthionine synthetase C-like 2 (LANCL2), a
therapeutic target for treating infectious diseases such as IFV-A infection. (235) The Ligustrum …

Therapeutic targets and potential agents for the treatment of COVID19

Y Wu, Z Li, YS Zhao, YY Huang… - Medicinal Research …, 2021 - Wiley Online Library
… for the treatment of COVID-19, several therapeutics and drugs … is to summarize three
therapeutic targets (proteases: RNA-… for further drug discovery to combat COVID-19. Both M pro …

Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… DUB and DUB-like proteases are under investigation as therapeutic targets for other
human diseases, but no inhibitors of these proteins have yet been approved 70 . Future …

Origin, potential therapeutic targets and treatment for coronavirus disease (COVID-19)

MS Nadeem, MA Zamzami, H Choudhry, BN Murtaza… - Pathogens, 2020 - mdpi.com
… The ongoing episode of coronavirus disease 19 (COVID-19) has imposed a serious threat
… The causative agent of COVID-19 is a novel coronavirus known as SARS-CoV-2. The virus …

COVID19 metabolism: Mechanisms and therapeutic targets

T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
… Here, we summarized the current understanding of the hallmarks of COVID19 metabolism.
… to uncover new therapeutic targets. The efficacy of metabolic inhibitors against COVID19 is …

Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets

DP Misra, V Agarwal, AY Gasparyan, O Zimba - Clinical rheumatology, 2020 - Springer
therapy. In this article, we provide the perspectives of a rheumatologist on COVID-19, …
We also discuss potential therapeutic targets for management of COVID-19, some of which …

Inflammasomes and pyroptosis as therapeutic targets for COVID-19

JKY Yap, M Moriyama, A Iwasaki - The Journal of Immunology, 2020 - journals.aai.org
coronavirus 2, we highlight the importance of the inflammasome pathway. We discuss available
pharmaceutical agents that targettarget for the treatment of severe coronavirus disease …

COVID-19 associated complications and potential therapeutic targets

JD Monpara, SJ Sodha, PK Gupta - European Journal of Pharmacology, 2020 - Elsevier
therapy. There … COVID-19. This review provides currently available information and insight
into pathophysiology of the disease, potential targets, and relevant clinical trials for COVID-19. …