[HTML][HTML] Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - … and targeted therapy, 2021 - nature.com
… factors are potential targets for antiviral therapy. Hence, in this study, the current therapeutic
strategies of COVID-19 have been classified into “target virus” and “target host” categories. …

Advances in sarcopenia: mechanisms, therapeutic targets, and intervention strategies

Y Zheng, J Feng, Y Yu, M Ling, X Wang - Archives of Pharmacal Research, 2024 - Springer
Sarcopenia is a multifactorial condition characterized by loss of muscle mass. It poses
significant health risks in older adults worldwide. Both pharmacological and non-pharmacological …

Molecular pathogenesis and interventional strategies for Alzheimer's disease: promises and pitfalls

S Bhute, D Sarmah, A Datta, P Rane… - ACS pharmacology & …, 2020 - ACS Publications
… The present review attempts to address the novel therapeutic targets of AD that might pave
the way for drug discovery using a known target and provide a successful pharmacotherapy …

[HTML][HTML] Insights into potential targets for therapeutic intervention in epilepsy

C Zavala-Tecuapetla, M Cuellar-Herrera… - International journal of …, 2020 - mdpi.com
… research to find novel therapeutic targets and to develop … Among these potential therapeutic
targets, we highlight … zinc supplementation as a therapeutic strategy to treat seizures, …

Novel targets for therapeutic intervention against ischemic brain injury

A Sun, J Cheng - Clinical neuropharmacology, 1999 - journals.lww.com
… has shed light on the development of neuroprotective therapy, Glycine site antagonism of
N-methyl-… In the future, the efficacy of these novel strategies should be continued in larger study …

[HTML][HTML] Novel therapeutic targets for epilepsy intervention

L Kambli, LK Bhatt, M Oza, K Prabhavalkar - Seizure, 2017 - Elsevier
… inflammatory targets like Interlukin-1β (IL-1β), Transforming Growth Factor β (TGF-β) and
their role along with inhibition strategy are explained in this review. Since mammalian target of …

[HTML][HTML] Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

WG Stetler-Stevenson - The Journal of clinical investigation, 1999 - Am Soc Clin Investig
… This understanding is providing novel therapeutic targets for … Current therapeutic approaches
targeting MMP activity utilize … discern what MMPs to target, and when to target them, with …

Targeting IAP proteins for therapeutic intervention in cancer

S Fulda, D Vucic - Nature reviews Drug discovery, 2012 - nature.com
… Among the therapeutic strategies that have been designed to target IAP proteins, the most
widely used … Alternative strategies include transcriptional repression and the use of antisense …

Endothelial cells at inflammatory sites as target for therapeutic intervention

GA Koning, RM Schiffelers, G Storm - Endothelium, 2002 - Taylor & Francis
… After identification of several candidate targeting molecules, therapeutic strategies should …
important therapeutic targets for drug targeting. In this review, some possible target receptors …

Therapeutic strategies for the treatment of tauopathies: Hopes and challenges

MR Khanna, J Kovalevich, VMY Lee… - Alzheimer's & …, 2016 - Elsevier
… potential targets for therapeutic intervention [35], as detailed further in the following section.
… and certain specific proteolytic products as possible therapeutic targets. However, the large …