Therapies for prevention and treatment of Alzheimer's disease

J Mendiola-Precoma, LC Berumen… - BioMed research …, 2016 - Wiley Online Library
Alzheimer’s disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout the …

Update on Alzheimer's disease therapy and prevention strategies

WV Graham, A Bonito-Oliva… - Annual review of …, 2017 - annualreviews.org
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …

Anti-amyloidogenic therapies: strategies for prevention and treatment of Alzheimer's disease

T Hamaguchi, K Ono, M Yamada - Cellular and Molecular Life Sciences …, 2006 - Springer
Deposition of amyloid β-protein (Aβ) in the brain is an early and invariant neuropathological
feature of Alzheimer’s disease (AD). The current search for anti-AD drugs is mainly focused …

Prevention of Alzheimer's disease: lessons learned and applied

JE Galvin - Journal of the American Geriatrics Society, 2017 - Wiley Online Library
… Even if these precision approaches alone are not successful in preventing AD, they may
greatly improve the likelihood of amyloid- or tau-specific therapies to reach their endpoints by …

Current and future therapy in Alzheimer's disease

RJ Van Marum - Fundamental & clinical pharmacology, 2008 - Wiley Online Library
… field of dementia is focused on Alzheimer’s dementia (AD), this review will focus on
pharmacological interventions in AD. Most disease-modifying therapies are based on the amyloid …

Update on disease-modifying/preventive therapies in Alzheimer's disease

JT Apter, K Shastri, K Pizano - Current Geriatrics Reports, 2015 - Springer
… capabilities of individuals afflicted with Alzheimer’s disease. In the near future, this research
will provide the answer to the cure and possible early prevention of Alzheimer’s disease. …

Pharmacological strategies for the prevention of Alzheimer's disease

PM Doraiswamy, GL Xiong - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
… , and the projected increase in prevalence of Alzheimer’s disease (AD) over the next 50
years makes a strong case for developing therapies that can prevent or delay the onset of AD. …

[HTML][HTML] Advances in the prevention of Alzheimer's Disease

S Sindi, F Mangialasche, M Kivipelto - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Alzheimer's disease (AD), the leading cause of dementia, has reached epidemic proportions,
with major social, medical and economical burdens. With no currently available curative …

New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge

L Piemontese - Neural regeneration research, 2017 - journals.lww.com
… and chronic diseases are more and more common. For several of these pathologies, only
few drugs have been available for therapies over the years. Alzheimer's disease (AD), for …

Developing effective Alzheimer's disease therapies: clinical experience and future directions

DR Elmaleh, MR Farlow, PS Conti… - … of Alzheimer's …, 2019 - content.iospress.com
Alzheimer’s disease (AD) clinical trials, focused on disease modifying drugs and conducted
… design aimed at improving our ability to identify novel therapies for this devastating disease. …