[HTML][HTML] Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study

H Yu, L Lin, Z Zhang, H Zhang, H Hu - … and targeted therapy, 2020 - nature.com
… the potential target for therapy of diseases. This … NF-κB pathway regulation and the potential
therapeutic application of inhibition of NF-κB signaling in cancer and inflammatory diseases. …

NFκB in liver diseases: a target for drug therapy

P Muriel - Journal of Applied Toxicology, 2009 - Wiley Online Library
… (inhibitor of κB); this interaction blocks the ability of NF-κB to translocate to nucleus. NFκB is
… to inhibit the activation of NFκB in the hepatoma cell line HepG2 (Saliou et al., 1998) and in …

Inhibition of NF-κB signaling as a strategy in disease therapy

TD Gilmore, MR Garbati - NF-kB in Health and Disease, 2010 - Springer
… these individual inhibitors again, we discuss here the general strategies for inhibition of
NF-κB, and provide a few examples of the use of NF-κB inhibitors for the treatment of disease. …

[HTML][HTML] Roles of NF-κB in cancer and inflammatory diseases and their therapeutic approaches

MH Park, JT Hong - Cells, 2016 - mdpi.com
… Thus, inhibiting NF-κB signaling has potential therapeutictherapy may have applications
to diseases where NF-κB activity is involved, including cancer, diabetes and heart disease [102,…

NF-κB signaling pathway and its therapeutic implications in human diseases

FH Sarkar, Y Li, Z Wang, D Kong - International reviews of …, 2008 - Taylor & Francis
… Administration of vitamin E leads to a slowing of disease progression, and the patients …
of Alzheimer's disease [Citation25], suggesting the importance of NF-κB activity in the disease

[HTML][HTML] NF-κB: a key role in inflammatory diseases

PP Tak, GS Firestein - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-κB activity
… IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. …

Roles of NF-κB in health and disease: mechanisms and therapeutic potential

ET Wong, V Tergaonkar - Clinical science, 2009 - portlandpress.com
… of NF-κB signalling in several human diseases, including cancers and chronic inflammatory
disorders. NF-κB-pathway-specific therapies are … as interventions of NF-κB-related ailments. …

The NF-kB pathway as a potential target for autoimmune disease therapy

S Bacher, ML Schmitz - Current pharmaceutical design, 2004 - ingentaconnect.com
… on the contribution of NF-κB to some selected autoimmune diseases which are discussed
… of NF-κB activation [68, 71]. While part of the elevated NFκB activity in Crohn's disease may …

NF-κB as a therapeutic target in inflammatory-associated bone diseases

TH Lin, J Pajarinen, L Lu, A Nabeshima… - Advances in protein …, 2017 - Elsevier
… These unique characteristics imply the great potential of NF-κB as a therapeutic target for …
This review will focus on the biological significance and therapeutic potential of NF-κB in bone …

NF-κB as a target for cancer therapy

D Melisi, PJ Chiao - Expert opinion on therapeutic targets, 2007 - Taylor & Francis
therapeutic outcomes that are controlled by NF-κB. In this review, the authors discuss the
rationale behind targeting NF-κB for cancer therapy… of some of the NF-κB inhibitors alone and in …