… One critical aspect of thromboinflammation is endothelial dysfunction, which is prominently
evident in multiple inflammatory diseases, including acute COVID-19 [18]. Studies involving …

… behave as key regulators in the nexus between inflammation, immunity and thrombosis. The
… upon activation of monocytes, is still elusive. Imbalance in cytokine homeostasis plays an …

… The other interesting finding in these studies is the dissociation in inflammation and … -19,
and other factors in addition to inflammation may sustain hypercoagulability. However, the …

… The complement system plays a key role in immunity facilitating pathogen elimination by …
characterized; that is, the role of PAR 1/4 for the binding of C4a to platelets remains elusive. …

… Stabilizing vulnerable, rupture-prone atherosclerotic plaques has long been an elusive aim
of … A key driver of plaque progression and instability is inflammation, with monocytes and …

… Lastly, it also remains elusive what exactly first causes the … the network between inflammation
and thrombosis. In reality, … spanning inflammation and thrombosis and identifying the key …

… inflammatory arthritis [50], demonstrating that plasma HK is a key mediator of inflammatory
… B1R is likely a key receptor that mediates the proinflammatory effect of bradykinin in arthritis. …

… thrombotic and pro-inflammatory pathways, and downstream … that we refer to as
thrombo-inflammation. Results of clinical … , therefore further anti-inflammatory treatments would …

… a high incidence of coagulopathy and venous thromboembolism that may contribute to the
… followed by a massive release of pro-inflammatory cytokines, which mediate the activation of …

… to infarct maturation remained elusive. Experimental evidence now … processes orchestrate
a ‘thrombo-inflammatory’ cascade in … 2008b), this appears not to be the key step in ischaemic …