The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
Timing the right treatment for the right phase of this disease is paramount, with correlations
… following COVID-19 infection can further develop to a fulminant cytokine storm which can …

The possible role of vitamin D in suppressing cytokine storm and associated mortality in COVID-19 patients

A Daneshkhah, V Agrawal, A Eshein, H Subramanian… - MedRxiv, 2020 - medrxiv.org
… Of particular note is that the time interval for the development of a substantial adaptive …
time course of COVID-19 mortality[10,23]. The reported potential role of ibuprofen in worsening …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
COVID-19. The review also portrays a question and debates: Can targeting cytokine storm
can be a feasible approach to combat COVID-… smokers are 1.4 times more prone to COVID-19 …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
… Thus, nodes of onset times may also affect host responsiveness of ARDS in COVID-19.
Therefore, identification of hyper-inflammatory subphenotypes of ARDS and focusing on patients …

Treatment of cytokine storm in COVID-19 patients with immunomodulatory therapy

L Yessayan, B Szamosfalvi, L Napolitano, B Singer… - Asaio …, 2020 - journals.lww.com
… inhibitors because he had chronic kidney stage 5 per our institutional policy at the time. Over
the subsequent 10 days, his respiratory failure progressed to severe ARDS and hypoxemia …

[HTML][HTML] Early identification of COVID-19 cytokine storm and treatment with anakinra or tocilizumab

A Langer-Gould, JB Smith, EG Gonzales… - International Journal of …, 2020 - Elsevier
… commonly referred to as cytokine storm. Tocilizumab and other … patients with COVID-19-related
cytokine storm (COVID19-CS). … for by COVID19-CS severity and/or duration at the time of …

[HTML][HTML] Cytokine storm of COVID-19 and its impact on patients with and without chronic liver disease

M Premkumar, CK Kedarisetty - Journal of Clinical and …, 2021 - ncbi.nlm.nih.gov
… It is time to reinterpret and define the cytokine storm. The role of T cells that exert protective
functions by reigning in on overactive innate immunity is important, as lymphopenia is …

Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

L Chen, G Wang, J Tan, Y Cao, X Long, H Luo… - … and Targeted Therapy, 2020 - nature.com
… the disparity in enrollment time (Supplementary Fig. S2a). The cytokine storm score of each
… identified chemokines and IL-6 as determinant cytokines in severe cytokine storm. The MCP-…

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
… excessive and prolonged cytokine/chemokine response known as “cytokine storms,” which
… Although studies reviewed in this manuscript provide evidence that “cytokine storms” and …

Specific cytokines in the inflammatory cytokine storm of patients with COVID-19-associated acute respiratory distress syndrome and extrapulmonary multiple-organ …

J Wang, X Yang, Y Li, J Huang, J Jiang, N Su - Virology journal, 2021 - Springer
… specific cytokines at admission and their changes over timecytokine storm experienced by
patients with severe COVID-19 … certain specific cytokines during the early stage of COVID-19 …