… Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (… tissue damage …

… cytokine storm induced by COVID-19. In addition, we suggest that the identification and
treatment of the cytokine storm … neutrophils into the lung tissue, which results in a cytokine storm. …

… tissue damage in acute pancreatitis have shown a number of inflammatory mediators to be
involved. The pathways of damage … to localized tissue destruction and distant organ damage. …

… that cytokine storms may aggravate tissue damage (43). Meanwhile, T lymphocyte cells were
excessively activated during the cytokine storm … The cytokine storm can directly damage the …

… Strategies for targeted treatment of various types of infection-induced cytokine storms are …
indicate that cytokine storm-targeted therapies can effectively alleviate tissue damage while …

… Coronaviruses stimulate the production of IL-6 and IL-1b which induce inflammatory … and
initiate cascades of cytokine storm [29,30]. The process by which cytokine storm is induced by …

… in patients with MODS: (1) the cytokine storms are the basic pathologic mechanism that
causes … Endothelial cell dysfunction is considered a precursor to tissue damage and end-organ …

… Continued endothelial activation results in multi-organ failure, regardless of pulmonary
tissue damage. We propose that targeting the endothelium may interrupt this cycle. Immuno-…

… cytokines and the induction of inflammatory cell death. These processes can contribute to
cytokine storm, tissue damage, … immunity driving cytokine storm and organ damage in patients …

… cytokine storm has arisen, conventional therapeutics may not be sufficient. Strategies to combat
this cytokine storm … of the cytokine storm, reducing the risk of tissue damage and allowing …