… -oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID-19?

FV Francisqueti-Ferron, JL Garcia, AJT Ferron… - Molecular and Cellular …, 2021 - Elsevier
… factor is synthetized by adipose tissue, the aim of this study was to test the hypothesis that
γOz attenuates the cytokine storm by modulating the PPAR-γ expression in the adipose tissue. …

[HTML][HTML] Covid-19 cytokine storm in pulmonary tissue: Anatomopathological and immunohistochemical findings

AFR dos Santos Miggiolaro, JSM Junior… - … Medicine Case Reports, 2020 - Elsevier
cytokine storm that will culminate on endothelial activation and consequently may cause
a Systemic Inflammatory Response Syndrome (SIRS) with multiple organ failure and death [9]. …

Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
… However, “cytokine storm” was initially coined in the early … , an allogenic response to foreign
tissue called graft vs host … to be significant sources of inflammatory cytokines during these …

Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

C Wang, J Xie, L Zhao, X Fei, H Zhang, Y Tan, X Nie… - …, 2020 - thelancet.com
… Immunohistochemical staining was performed on the slides of lung tissues from two patients.
inflammatory cytokines secreted by alveolar macrophages including IL-6, IL-10 and TNFα. …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
… immune-mediated tissue damage versus wound healing and tissue repair response [12,13]. …
immune system and initiates an inflammatory cytokine storm, but long-term loss of control in …

Dynamics of a cytokine storm

HH Yiu, AL Graham, RF Stengel - 2012 - journals.plos.org
Cytokines allow context-dependent … to cytokine production are destabilized, a "cytokine
storm" (or hypercytokinemia) can result, producing unbridled inflammation within tissues and key …

Regulation of inflammatory cytokine storms by mesenchymal stem cells

L Wang, Y Li, M Xu, Z Deng, Y Zhao, M Yang… - Frontiers in …, 2021 - frontiersin.org
… , 44), which diffuse to intercellular spaces or tissue fluids and regulate adjacent target cells.
EVs … of the local inflammatory response and reduces tissue inflammatory injury. The types of …

Targeting purinergic receptors to suppress the cytokine storm induced by SARS-CoV-2 infection in pulmonary tissue

JLB Simões, HF Basso, GC Kosvoski, J Gavioli… - International …, 2021 - Elsevier
… However, as there is no tightening of the attack, the cycle is replenished, exaggerating
the inflammatory markers and generating the cytokine storm, which can cause ARDS, organ …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… cascade, generating a cytokine storm. Hemophagocytic … and other tissues of patients
affected by cytokine storms, maybe … of the cytokine storm and the thrombo-inflammatory state …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
… of the cytokine storm has not … inflammatory cytokine overproduction are addressed in this
work. The virus-mediated down-regulation of ACE2 causes a burst of inflammatory cytokine