Tissue remodelling in pulmonary fibrosis

L Knudsen, C Ruppert, M Ochs - Cell and Tissue Research, 2017 - Springer
pulmonary fibrosis used in translational research into account, we will discuss aspects in the
pathogenesis of pulmonary fibrosis … trigger of pro-fibrotic remodelling and the relevance of a …

Therapeutic targets in lung tissue remodelling and fibrosis

G Liu, AM Philp, T Corte, MA Travis, H Schilter… - Pharmacology & …, 2021 - Elsevier
… involving tissue remodelling and fibrosis are major features of many pulmonary diseases, …
of tissue remodelling that results in symptoms and impaired lung function in these diseases. …

Vascular remodelling in the pathogenesis of idiopathic pulmonary fibrosis

S Barratt, A Millar - QJM: An International Journal of Medicine, 2014 - academic.oup.com
… The finding of elevated serum levels of endostatin in IPF led to the speculation that endostatin
may be released by activated tissue fibroblasts and contribute directly to fibrotic process. …

[HTML][HTML] Idiopathic pulmonary fibrosis: immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic …

NJ Lomas, KL Watts, KM Akram… - … journal of clinical and …, 2012 - ncbi.nlm.nih.gov
… This study explored the cellular and biological interrelationships involved in Idiopathic
Pulmonary Fibrosis (IPF) lung tissue remodelling using immunohistochemical analysis. …

Matrix abnormalities in pulmonary fibrosis

C Upagupta, C Shimbori, R Alsilmi… - European Respiratory …, 2018 - Eur Respiratory Soc
… The recruitment and accumulation of myofibroblasts plays a major role in aberrant tissue
remodelling and fibrosis. The intrinsic role that the ECM plays in driving progressive …

Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition

AV Gaikwad, W Lu, S Dey, P Bhattarai… - ERJ Open …, 2022 - Eur Respiratory Soc
pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic … -based quantitation of pulmonary
arterial remodelling in IPF … for pulmonary arteries was conducted in NC and IPF tissues. …

Inflammation‐associated remodelling and fibrosis in the lung–a process and an end point

WAH Wallace, PM Fitch, AJ Simpson… - International Journal …, 2007 - Wiley Online Library
remodelling’ is a better description for this process as it reflects changes in tissue organization
that may or may not progress to ‘fibrosis’ … Pulmonary fibrosis is the presence of scarring in …

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

SG Royce, Y Moodley, CS Samuel - Pharmacology & therapeutics, 2014 - Elsevier
pulmonary disease, acute respiratory distress syndrome and idiopathic pulmonary fibrosis.
… progressive lung injury that results in tissue remodelling or fibrosis. Acute disease may often …

Architectural remodelling in acute and chronic interstitial lung disease: fibrosis or fibroelastosis?

EM Negri, GS Montes, PHN Saldiva… - …, 2000 - Wiley Online Library
… : Pulmonary fibrosis in acute and chronic lung disease has been much investigated, but
little attention has been directed at the elastic tissue in these situations. Our aim was to verify …

Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis

G Tjin, ES White, A Faiz, D Sicard… - Disease models & …, 2017 - journals.biologists.com
… Although increased collagen deposition is well appreciated in fibrotic lung tissues, this study
identifies, for the first time, alterations in the fibrillar organization of the collagen fibres in IPF …