… Inflammation and tissue remodelling with pathologic fibrosis are common consequences
of Th2 responses in the lung and other organs. IL-13 and TGF-β1 are frequently co-expressed …

… pulmonary fibrosis and systemic sclerosis. Asthma treatment with inhaled corticosteroids does
not fully prevent airway remodelling and … showed that fibrocytes migrate to fibrotic tissue in …

… transition,26 ,27 endothelial-to-mesenchymal transition,28 ,29 fibroblast and smooth muscle
proliferation and myofibroblast transformation,5 and in vascular and lung tissue remodelling …

… of abnormal and normal lung tissue visible side by side, without transition zones. There is
architectural destruction, dense fibrosis, and areas of relatively normal lung tissue (asterisk). …

… (ECM) remodelling of the lungs related to lung function decline in pulmonary fibrosis (PF)…
A range of non-invasive serological biomarkers, reflecting tissue remodelling, and fibrosis …

… that were suggestive of pulmonary fibrosis but had no identifiable cause. At that time,
associations between pulmonary fibrosis and postinfection fibrosis, pneumoconiosis, radiation …

Background We have previously reported arterial remodelling in patients with idiopathic
pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) …

… remodelling Fibroblasts and myofibroblasts play a central role in synthesis, deposition and
remodelling … matrix is the hallmark of the aberrant tissue remodelling in IPF. The loss of a …

… areas composed mainly of dense acellular collagen; and 3) the presence of honeycomb
lesions, which are abnormal dilated airspaces with walls composed of fibrotic tissue, lined by an …

… up regulation in idiopathic pulmonary fibrosis associated PH … pulmonary vascular but also
whole organ remodelling in the … in the ECM during tissue remodelling and therefore qualify as …