… -fibrotic phenotype has been demonstrated to contribute to the development of idiopathic
pulmonary fibrosis (… impairment and the development of lung fibrosis. Furthermore, aging is a …

… degradation, which in turn produces tissue remodelling. Understanding the main signal … ,
plays a main role in lung tissue remodeling in pulmonary fibrosis [144]. Apart from pirfenidone, …

… In addition, TIMP-4 mRNA and protein were detected in epithelial and plasma cells in
lungs of patients suffering from idiopathic pulmonary fibrosis, whereas this gene is barely …

… pulmonary fibrosis while MMP3-deficient mice were protected from bleomycin-induced
pulmonary fibrosis … wound repair and tissue remodelling characteristic of advanced IPF lesions. …

… lung tissue remodelling in asthma, bronchiectasis, fibrosis and chronic obstructive pulmonary
… The focus of this review is the role of muscarinic receptors in lung tissue remodelling as it …

… A failure to appropriately regulate the adaptive immune response could be detrimental to
the host, and predispose to chronic inflammation and damage and tissue remodelling with …

… Idiopathic pulmonary fibrosis (IPF) is the most common and … the lung irreversible remodelling
of tissue architecture takes … , abnormal fibrosis and severe tissue remodelling. In previous …

… Iron accumulation resulted crucial for macrophage activation, inducing inflammatory,
tissue remodelling and angiogenic processes in IPF [25]. A very recent paper underlined the …

… and remodelling, and is regulated by a wide variety of growth factors and cytokines. In
this condition, tissue remodelling appears to be essential for recovery of the organ function. …

… These proteases may propagate abnormal tissue remodelling in IPF by damage to
alveolar basement membranes. An alternative hypothesis suggests that enhanced protease …