… This was accompanied by significantly elevatedconcentrations of nitrite and nitrate in the
plasma and expression of high levels of nitric oxide (NO) synthase activity in the lungs, heart, …

… Nitric oxide (NO), first identified as endothelium-derived relaxing factor (EDRF), is a free …
IL-l), interferony (IFN-y), tumor necrosis factor-a (TNF-a) induce iNOS expression in various cells …

… nitric oxide (NO) metabolites and to determine whether there is association between serum
concentrations tumor necrosis factor (TNF)-α and TNF … NO metabolites and of TNF-α and its …

… of nitric oxide on LPSdependent TNF-a production by human neutrophils were examined to
explore mechanisms by which endotheliumderived nitric oxide … The ability of nitric oxide to …

… to be both a TNF-α-dependent-iNOS-dependent killing pathway as well as a TNF-α-dependent-…
Tumor necrosis factor α plays a major role in the control of mycobacterial infection both in …

… a lesser extent with TNF-α, induced a significant trypanocidal activity. Furthermore, TNF-α
had a … the production of nitric oxide (NO) by macrophages, whereas TNF-α was less effective, …

… Significantly higher levels of IFN-y and TNF-a were found in the sera of IL-12-treated mice,
which correlated with high levels of the nitric oxide (NO) metabolite, NO,-. Furthermore, CD4+ …

… Some of the samples were loaded with the nitric oxide synthase (NOS) inhibitor L-NAME (0.7
mmol/l) 30 min prior to DAF-2/DA administration. Care was taken to prevent exposure to …

… effects on the production of TNF-alpha (TNF-α) and nitric oxide (NO) by lipopolysaccharide
(… line N9 to LPS increased their release of TNF-α and NO, which was significantly inhibited by …

… We now show that TNF-o~ induces a time- and dose-dependent cytotoxic effect on cultured
… This TNF-induced cytotoxicity, which is preceded by increased production of nitric oxide (NO)…