Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis

VS Patil, A Madrigal, BJ Schmiedel, J Clarke… - Science …, 2018 - science.org
transcriptomic and T cell antigen receptor (TCR) analysis of circulating human CD4-CTLs. …
S8A) were previously found to be CD4-CTL precursors by full-length transcriptome analysis, …

Transcriptome and proteome expression in activated human CD4 and CD8 T-lymphocytes

FB Stentz, AE Kitabchi - Biochemical and biophysical research …, 2004 - Elsevier
… in activated and non-activated CD4 and CD8 lymphocytes on non-… analysis of gene
expression (transcriptome) and proteins translated (proteome) in activated vs non-activated CD4

Adaptation of human CD4+ T cells to pathophysiological hypoxia: a transcriptome analysis

T Gaber, T Häupl, G Sandig, K Tykwinska… - The Journal of …, 2009 - jrheum.org
… Next, we analyzed the effect of hypoxia on the transcriptome of CD4+ T cells in more detail.
Evaluation of expression pattern was restricted to those sequences that exhibited a ≥ 2-fold …

Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma

E Tsitsiou, AE Williams, SA Moschos, K Patel… - Journal of Allergy and …, 2012 - Elsevier
… We sought to use transcriptomics to determine the activation state of circulating CD4 + and
… in the CD4 + and CD8 + T cells from patients with severe asthma, we analyzed the changes …

Transcriptomic analysis of CD4+ T cells reveals novel immune signatures of latent tuberculosis

JG Burel, CS Lindestam Arlehamn, N Khan… - The Journal of …, 2018 - journals.aai.org
… Whole-blood transcriptomic studies in TB have proven useful … An alternative strategy is to
perform transcriptomic analysis of … performed transcriptomic studies on sorted memory CD4 T …

CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case–control study

H Ye, J Zhang, J Wang, Y Gao, Y Du, C Li… - Arthritis research & …, 2015 - Springer
CD4 T-cell transcriptome analysis by comparing RA patients to healthy controls. We found a
great difference in gene expression profiling of CD4 … signaling pathways in CD4 T cells from …

MiRNome and transcriptome aided pathway analysis in human regulatory T cells

MH Albert, J Mannert, KK Fleischmann… - Genes & …, 2014 - nature.com
… program that defines Treg, we compared their transcriptomic profile (miR and mRNA)
with … Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- …

A transcriptome-based model of central memory CD4 T cell death in HIV infection

G Olvera-García, T Aguilar-García, F Gutiérrez-Jasso… - BMC genomics, 2016 - Springer
… whole transcriptome for all differentially expressed genes in the following pair-wise comparisons
of CD4 T cell subpopulations from controls: T CM vs. T N , T EM vs. T CM, and T EM vs. …

Transcriptome profiling of human FoxP3+ regulatory T cells

R Bhairavabhotla, YC Kim, DD Glass, TM Escobar… - Human immunology, 2016 - Elsevier
The major goal of this study was to perform an in depth characterization of the “gene signature”
of human FoxP3 + T regulatory cells (Tregs). Highly purified Tregs and T conventional …

Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage

G Chan, ER Bivins-Smith, MS Smith… - The Journal of …, 2008 - journals.aai.org
… The rapid production of numerous cytokines is characteristic of a classical M1 monocyte/macrophage
activation/differentiation lineage, and our transcriptome analysis indicates that …