Integrated lipidomics, transcriptomics and network pharmacology analysis to reveal the mechanisms of Danggui Buxue Decoction in the treatment of diabetic …

L Sun, Z Yang, W Zhao, Q Chen, H Bai, S Wang… - Journal of …, 2022 - Elsevier
Transcriptomics analyses were carried out using RNAseq. The possible molecular mechanism
was unraveled by network pharmacology… and transcriptomics, and network pharmacology

Integrating network pharmacology and transcriptomic validation to investigate the efficacy and mechanism of Mufangji decoction preventing lung cancer

F Gao, Y Niu, L Sun, W Li, H Xia, Y Zhang… - Journal of …, 2022 - Elsevier
… Here, we employed the strategy of integrating network pharmacology with transcriptomics
analysis to elucidate the mechanisms of MFJD, our results unveiled the potential ingredients …

Comparative transcriptomics and network pharmacology analysis to identify the potential mechanism of celastrol against osteoarthritis

S Dai, H Wang, M Wang, Y Zhang, Z Zhang, Z Lin - Clinical Rheumatology, 2021 - Springer
… inflammation, which just fits the network concept of network pharmacology. In closing,
this study applied the combination of transcriptomics, network pharmacology, and computer-aided …

[HTML][HTML] … decoction suppresses rat liver fibrosis involved in an apoptosis regulation mechanism based on network pharmacology and transcriptomic analysis

FF Cai, YQ Bian, R Wu, Y Sun, XL Chen… - Biomedicine & …, 2019 - Elsevier
… In the present work, we performed a network pharmacology approach, combined transcriptomics
to identify the active components and their targets of YCHD treated liver fibrosis. Further…

Network pharmacology and transcriptomics to determine Danggui Yifei Decoction mechanism of action for the treatment of chronic lung injury

J Guo, J Liang, Z Guo, X Bai, H Zhang, N Zhang… - Journal of …, 2024 - Elsevier
network pharmacology together with transcriptomics was used to predict potential biological
targets. Western blot analysis … of network pharmacology and transcriptomics could effectively …

Network Pharmacology Integrated with Transcriptomics Deciphered the Potential Mechanism of Codonopsis pilosula against Hepatocellular Carcinoma

Z Liu, Y Sun, H Zhen, C Nie - Evidence‐Based Complementary …, 2022 - Wiley Online Library
… In this study, we integrated transcriptomics and network pharmacology to understand the
mechanisms of Codonopsis pilosula in treating HCC. The differentially expressed genes (DEGs…

… the potential mechanism of Astragalus membranaceus improving prognosis of hepatocellular carcinoma by combining transcriptomics and network pharmacology

Z Liu, H Ma, Z Lai - BMC complementary medicine and therapies, 2021 - Springer
Network pharmacology is a multidisciplinary approach that integrates systems biology,
bioinformatics and pharmacology. It … , we combined transcriptomics and network pharmacology to …

Integrated network pharmacology, metabolomics, and transcriptomics of Huanglian-Hongqu herb pair in non-alcoholic fatty liver disease

X Zhang, J Zhang, Z Zhou, P Xiong, L Cheng… - Journal of …, 2024 - Elsevier
… findings from network pharmacology, transcriptomics, and molecular docking, we refined the
scope of our study to focus solely on the PPAR signaling pathway for subsequent analyses. …

Exploration the active compounds of Astragali Radix in treatment of adriamycin nephropathy by network pharmacology combined with transcriptomic approach

AP Li, SS He, WN Zhang, LC Zhang, YT Liu, K Li… - Journal of …, 2020 - Elsevier
… In the current study, a network pharmacology combined with transcriptomic analysis method
… of AN, we combined network pharmacology with known transcriptomics results. Finally, a CI …

Network pharmacology of ginseng (Part II): The differential effects of red ginseng and ginsenoside Rg5 in cancer and heart diseases as determined by transcriptomics

A Panossian, S Abdelfatah, T Efferth - Pharmaceuticals, 2021 - mdpi.com
… the effects of differently expressed genes on cellular and physiological functions in
organismal disorders and diseases using a network pharmacology approach to transcriptomics. …