… efficient than AAV2 in the nonhuman primate brain, resulting in a far greater number of cells
transduced for … Using a viral vector with greater efficiency at transducing the desired cell type …

… To understand the distribution of AAV1 in various regions of the primate brain, we targeted
three regions: the striatum, corona radiata, and basal forebrain. The gray matter of the …

… been isolated from nonhuman primate tissues. In this study, transduction obtained with AAV
… AAV8, another nonhuman primate isolate previously shown to perform well in mammalian …

… efficiencies of different viral vectors carrying different promoters and serotypes in non-human
primates (… Serotype-dependent transduction efficiencies of recombinant adeno-associated …

… Of these 3 methods, transduction efficiency is the easiest to … demonstrated the relative
transduction efficiency of AAV8 > … efficiency of AAV2/8 > AAV2/5 > AAV2/2 in the primate brain. …

… protein (eGFP) in the nonhuman primate brain was evaluated 4 weeks after injection of …
primate brain and the extent of vector distribution within the brain 4 weeks after transduction …

… –brain barrier (BBB) and efficiently transduce cells of the central nervous system (CNS).
However, in the adult CNS, transduction … achieving widespread CNS transduction is a common …

… mostly glial transduction after … in primates confirmed the preliminary results observed in
mice with a global neuronal and glial brain transduction but with a preferentially glial transduction…

… transduction of non-human primate brain … transduction that included neurons in deep cortical
layers, deep cerebellar nuclei, several subcortical regions, and motor neuron transduction …

… brain regions of both hemispheres in two monkeys (M10 and M37) to determine their
transduction efficiency … insights into the transduction capacity of viral vectors in primates, it has its …