Transcription factor AP-2γ stimulates proliferation and apoptosis and impairs differentiation in a transgenic model

R Jäger, U Werling, S Rimpf, A Jacob… - Molecular cancer research, 2003 - AACR
… The AP-2γ transgenic mice described in this … of AP-2 transcription factors in mammary
cancer, that is, by intercrossing the LTRγ transgenic mice with oncogene-bearing transgenic mice. …

A distal region of the human TGM1 promoter is required for expression in transgenic mice and cultured keratinocytes

MA Phillips, BA Jessen, Y Lu, Q Qin, ME Stevens… - BMC dermatology, 2004 - Springer
… of the TGM1 promoter in transgenic mice fed a normal diet … , which includes both the AP1
and CRE regulatory elements that … to eliminate the AP1 site (TG1.1) or both the AP1 and CRE …

Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine

MC Peakman, C Colby, LI Perrotti, P Tekumalla… - Brain research, 2003 - Elsevier
… of the Jun family to form active AP-1 transcription factor complexes. In the present study, we
took advantage of this property and generated transgenic mice, using the tetracycline gene …

Exocrinopathy resembling Sjögren's syndrome in HTLV-1 tax transgenic mice

JE Green, SH Hinrichs, J Vogel, G Jay - Nature, 1989 - nature.com
… regulatory element known as the AP-1 site*"":"*". Yeast GCN4 protein binds as a homodimer
to target sequences that are indistinguishable from AP-1 sites". Extensive analysis indicates …

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300

AE Horvai, L Xu, E Korzus, G Brard… - Proceedings of the …, 1997 - National Acad Sciences
… hGH transgenes. (A) SR–hGH fusion genes used to generate transgenic mice are illustrated,
indicating the approximate positions of binding sites for AP-1, ets2, and PU.1 proteins. …

Life without white fat: a transgenic mouse

J Moitra, MM Mason, M Olive, D Krylov… - Genes & …, 1998 - genesdev.cshlp.org
… A-ZIP/F also inhibited the DNA binding of AP-1, a heterodimer of the Fos and Jun B-ZIP
domains. This promiscuous inhibition becomes zipper-specific if the acidic extension is placed …

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

R Zenz, R Eferl, C Scheinecker, K Redlich… - Arthritis research & …, 2008 - Springer
AP-1 were initially studied in mouse development as well as in the whole organism through
conventional transgenictransgenic mice expressing Fra-1 in osteoblasts [12]. Ablation of Fra-…

Dispensable role of the NF-χB sites in the UV-induction of the HIV-1 LTR in transgenic mice

A Zider, B Mashhour, P Fergelot, G Grimber… - Nucleic acids …, 1993 - academic.oup.com
mice epidermal extracts, that the NF-xB sites of the HIV-1 LTR were one of the targets of the
UV Induction. The Sp-1 sites and the potential AP-1 … , we generated transgenic mice carrying …

Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

LM Robertson, TK Kerppola, M Vendrell, D Luk… - Neuron, 1995 - cell.com
… We developed transgenic mice carrying fos-lacZ fusion genes with clustered point … element,
the serum response element, the los AP-1 site, and the calcium/cAMP response element. …

Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet

A Bhattacharya, B Chandrasekar, MM Rahman… - Biochemical and …, 2006 - Elsevier
… fat-1 transgenic mice on CR diet strongly inhibit AP-1 activity, … -κB and AP-1 activities was
noted in fat-1/CR mice, our results … first time that fat-1 transgenic mice on CR diet suppress LPS-…