… of AP-12 to cross the BBB, improve spatial learning and memory in both mice strains, induce
anxiolytic action in transgenic mice, … The present study investigated the ability of AP-12: 1) to …

… A-ZIP/F also inhibited the DNA binding of AP-1, a heterodimer of the Fos and Jun B-ZIP
domains. This promiscuous inhibition becomes zipper-specific if the acidic extension is placed …

… AP-1 were initially studied in mouse development as well as in the whole organism through
conventional transgenic … transgenic mice expressing Fra-1 in osteoblasts [12]. Ablation of Fra-…

… (NF-[Kappa]B mice), or PMA (AP-1 mice) also elicited … AP-1 transcription factor, RPA was
performed at 72 h on the lungs of AP-1 mice exposed to silica by intratracheal instillation (Fig 1, …

… The transgenic mice show that ectopic expression of Tcfap2c is not tolerated. Due to the
phenotype observed, iTcfap2c-mice represent a model system to study liver failure. In intestine, …

… of the Jun family to form active AP-1 transcription factor complexes. In the present study, we
took advantage of this property and generated transgenic mice, using the tetracycline gene …

… transgenic mice. We further show that the expression and activity of three transcription factors
(NF-κB, AP… This study reveals that the transgenic mouse line 3445 might be a useful model …

… We attempted to obtain homozygous transgenic mice in the two lines (AP-2 and -3) in order
… in fat-1 transgenic mice, as we were unable to produce homozygous transgenic lines and the …

… in which abnormalities in transgenic mice lacking JunB expression, specifically in the myeloid
lineage, were demonstrated [69]. These mice develop a transplantable myeloproliferative …

… -length human PS-1 protein in transgenic mice but not in control mice, and we confirmed
expression of human PS-1 N-terminal … A P value < 0.05 was considered statistically significant. …