… Here, we determined that K18-hACE2 transgenic mice show a significant upregulation in …
spatiotemporal analysis of SARS-CoV-2 infection in the K18-hACE2 transgenic murine model …

… Moreover, K18 hACE2 transgenic mice represent an … and/or treatment of SARS-CoV-2
infection, including recently … K18 hACE2 transgenic mouse model for SARS-CoV-2 infection. …

… For a pilot study, we infected in two Tg + mice of different genetic backgrounds obtained … ,
we succeeded in establishing a transgenic mouse model for MERS-CoV infection and disease. …

… in a complete inhibition of MERS pseudovirus infection (E and G) or MERS-CoV-induced
CPE (F) in at least 50% of the wells (NT 50 ). Mouse sera from 2 and 6 months were used for …

… Therefore, we performed an in vivo study using a SARS-CoV-2 infected hACE2 transgenic
mouse model and evaluated the potential efficacy of the drugs NTV, RDV and MPV and their …

… The resistance of WT mice to ancestral SARS-CoV-2 infection made transgenic hACE2 mice
one of … Considering the survival rate, 2 out of 16 B.1-infected transgenic mice met humane …

… Using transgenic mice expressing human angiotensin-… Many of the SARS-CoV-2 antigen
positive neurons of mice in … of virus entry via the olfactory bulb, as confirmed in both mice [42…

… and small molecules targeting the SARS-CoV-2 Spike protein interaction with ACE2. Since
… transgenic animal models expressing human ACE2, such as the hACE2 transgenic mouse, …

… groups have developed mice transgenic for the human SARS-CoV or MERSCoV receptors,
… K18-hACE2 transgenic mouse has also been used to study SARS-CoV-2 pathogenesis and …

… Whereas many COVID-19 vaccines focus on … mice, we identified a dominant CD8 T cell
SARS-CoV-2 nucleoprotein epitope. Infection of human ACE2 transgenic mice with SARS-CoV-2 …