… , safety and efficacy profiles of drugs. This presents several key questions for drug development,
including which transporters are clinically important in drug absorption and disposition, …

… on renal drug transporters and their impact on drug elimination, DDIs, and drug development.
… Although reabsorptive transporters are also involved in the renal handling of drugs, this …

… global drug development. This review discusses the role of transporters in drug development
with a focus on methodologies in assessing transporter-mediated drug-drug interactions, …

… , 7 on transporter–drug interactions. Transporter-related challenges in drug development
were highlighted… The ITC discussed additional clinically relevant transporters and best-practice …

… During its fourth transporter workshop in 2021, the International Transporter Consortium (ITC…
relevant transporters for drug development. Previously highlighted and new transporters …

… Drug interactions with key membrane transporters are routinely assessed for central nervous
system (CNS) drug … the wider drug discovery. But, there is interest in utilizing membrane …

… drugs. A range of topics including computational modeling of drug-transporter interactions
and emerging transporters … recent advances in transporters in drug development and include …

… for in vitro evaluation of transporter-based interactions that may … of transporters in drug
development.The ITC organized a Critical Path Transporter Workshop, cosponsored by the Drug …

… transporters during drug development. THE FDA’S RECOMMENDATIONS ON TRANSPORTER
DRUG … Evaluation of transporters during drug development and after approval is an in…

… was to discuss transporters of … transporters into the practice of drug development. The authors
of this article formed a working group to reach consensus on emerging drug transporters of …