Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection

Z Bahari, Z Jangravi, H Ghoshooni, MR Afarinesh… - Inflammation …, 2021 - Springer
… as a potential approach for the treatment of cytokine storm in severe cases of COVID-19.
One possible limitation of immunosuppressant therapy is their inhibitory effects on host anti-viral …

Current pharmacological treatments for COVID‐19: What's next?

C Scavone, S Brusco, M Bertini… - … of pharmacology, 2020 - Wiley Online Library
… and dry cough, while severe cases frequently cause pneumonia, … The mechanism of action,
main safety concerns and drugdrug … for the treatment of COVID-19 are reported in Table 1. …

Pharmacological treatment of chronic pain–the need for CHANGE

G Varrassi, G Müller-Schwefe, J Pergolizzi… - … medical research and …, 2010 - Taylor & Francis
pharmacological options available to manage these different pain mechanisms offers the
promise of better treatment … , but in 70% of these cases the therapy had to be changed because …

Network pharmacology: curing causal mechanisms instead of treating symptoms

C Nogales, ZM Mamdouh, M List, C Kiel… - … in pharmacological …, 2022 - cell.com
… and the ‘one disease–one target–one drug’ dogma obstruct innovation in the most profound
… arm, network pharmacology, revolutionize how we define, diagnose, treat, and, ideally, cure

Eosinophilic inflammation: An appealing target for pharmacologic treatments in severe asthma

A Vatrella, A Maglio, C Pelaia, L Ciampo, G Pelaia… - Biomedicines, 2022 - mdpi.com
… of most cases of severe asthma and considering that severepharmacological treatment of
patients with severe asthma. … their receptor mechanisms [166]; this drug is effective in severe

Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review

JM Sanders, ML Monogue, TZ Jodlowski, JB Cutrell - Jama, 2020 - jamanetwork.com
mechanism (mediator). I would be interested in a meta-analysis that surveyed all the potential
causal mechanisms, … a case report (written in Japanese) describing 2 clinical cases who …

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

GG Graham, MJ Davies, RO Day, A Mohamudally… - …, 2013 - Springer
… The apparent COX-2 selectivity of action of paracetamol is shown by its … As is the case with
the NSAIDs, including the selective COX-2 … Patients in severe cancer pain should be treated

Traditional pharmacological treatments for spasticity part II: general and regional treatments

JM Gracies, P Nance, E Elovic… - Muscle & Nerve …, 1997 - Wiley Online Library
… proven antispastic action. This chapter reviews the pharmacology, physiology of action, dosage,
… In cases where spasticity is satisfactorily treated by a dose which provokes symptomatic …

Metabolic side effects of antipsychotic drug treatmentpharmacological mechanisms

GP Reynolds, SL Kirk - Pharmacology & therapeutics, 2010 - Elsevier
Case-control studies of drug-naive patients with a first episode of psychosis in their mid-twenties
provide no indication of an increase in glucose intolerance or other indicators of the …

Remdesivir for COVID-19: A review of pharmacology, mechanism of action, in-vitro activity and clinical use based on available case studies

KC Badgujar, AH Ram, R Zanznay… - Journal of Drug …, 2020 - jddtonline.info
… features, mechanism of infectivity and use of drug to curedrug is approved by FDA to use
against COVID-19 treatment, … -drug (GS-5734) can be effectively used in the treatment of …