… The landscape of treatment options for elderly GBM patients has changed substantially over
… options based on patient age and KPS. Until further treatment advances are made for GBM …

… Fourth, the study results apply to the population treated (that is, patients 70 years old) and …
to treat the large group of elderly patients with GBM (estimated at 20% of all patients with GBM; …

… treatment in the management of patients with glioblastoma since the 1970s and the combination
of both doubles overall survival in patients … The prognosis of patients with glioblastoma …

… latest advances in treatment for glioblastoma and future directions … patients, and has a more
aggressive clinical course. Conversely, IDH-mutant glioblastoma or secondary glioblastoma …

… can only partially rely on robust data when it comes to treatment decisions. In the following,
we summarize the current knowledge on treatment options for elderly glioblastoma patients. …

… Health Organization (WHO) grade IV diffuse glioma (or glioblastoma [GB]), the most common
adult … The first known surgical operation to resect a glioma was performed by Dr Rickman J. …

… into account the patient’s functional status, tumor burden, and prior treatments. If … patients
with good functional status. Ongoing investigations of novel treatment options for glioblastoma …

… of older patients with GB in the absence of definitive randomized trials for many of the treatment
options? As the patterns of care studies demonstrate, clinicians and patients are making …

… Because the EORTC-NCIC study included only patients aged 18–… treatment options for
elderly patients. As age is an important prognostic factor in GBM, the prognosis of elderly patients …

… glioblastoma. Depending on local availability, the combination of bevacizumab and lomustine
is a treatment option in particular in patients … is now used in symptomatic patients at later …