Regulation of Skeletal Muscle Plasticity by Glycogen Synthase Kinase-3beta;: A Potential Target for the Treatment of Muscle Wasting

KJP Verhees, NAM Pansters… - Current …, 2013 - ingentaconnect.com
… the context of multimodal treatment strategies aimed at the … muscle mass plasticity for the
treatment of muscle wasting. Keywords: Muscle plasticity, Glycogen synthase kinase-3, muscle

Recent developments in the field of cachexia, sarcopenia, and muscle wasting: highlights from the 11th Cachexia Conference

N Ebner, SD Anker… - … , Sarcopenia and Muscle, 2019 - Wiley Online Library
… From basic science, new therapeutic targets were shown including RNAsome, piRNAs, …
of muscle wasting and cachexia and the potential epigenetic treatment targets were presented …

Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies

N Ebner, L Steinbeck, W Doehner, SD Anker… - 2014 - Springer
target for the treatment of muscle atrophy. … and treatment of muscle wasting in patients with
cancer (POWER)” evaluating enobosarm for the prevention and treatment of muscle wasting

Blocking extracellular activation of myostatin as a strategy for treating muscle wasting

M Pirruccello-Straub, J Jackson, S Wawersik… - Scientific reports, 2018 - nature.com
… -like syndrome with muscle wasting and fat loss 9 . Because of the well-established impact
of myostatin signaling on muscle mass, a number of agents that target the myostatin signaling …

Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting

D Nury, C Doucet, O Coux - BMC biochemistry, 2007 - Springer
… potential for pharmaceutical drugs able to treat muscle wasting when it becomes deleterious.
This review presents an overview of the main pathways contributing to UPS activation in …

Recent developments in the field of cachexia, sarcopenia, and muscle wasting: highlights from the 12th Cachexia Conference

N Ebner, SD Anker… - … , sarcopenia and muscle, 2020 - Wiley Online Library
… Activin and Act-R ligands are becoming increasingly important as triggers of muscle
wasting and as pharmacological targets to treat cachexia; however, because follistatin alone is …

Muscle wasting in cancer: opportunities and challenges for exercise in clinical cancer trials

CM Fairman, S Lønbro, TD Cardaci… - JCSM rapid …, 2022 - Wiley Online Library
… exercise required to sufficiently target muscle mass, particularly in a … trials to target muscle
wasting is provided in Table 1. … the impact of cancer treatments on muscle wasting using single …

β2-Adrenergic agonists and the treatment of skeletal muscle wasting disorders

OR Joassard, AC Durieux, DG Freyssenet - The international journal of …, 2013 - Elsevier
… of β2-agonists in the treatment of muscle wasting. This review examines the … muscle wasting,
and the potential interest of β2-agonist administration for the treatment of muscle wasting in …

Association of skeletal muscle wasting with treatment with sorafenib in patients with advanced renal cell carcinoma: results from a placebo-controlled study

S Antoun, L Birdsell, MB Sawyer, P Venner… - Journal of clinical …, 2010 - ascopubs.org
… Large fat reserves notwithstanding, muscle wasting continues. The reported … in the TARGET
study, so muscle wasting may simply be a consequence of disease progression. Muscle loss …

Sex differences in muscle wasting

LJ Anderson, H Liu, JM Garcia - Sex and gender factors affecting …, 2017 - Springer
… In humans, testosterone targets satellite cells to prevent the age-related myocyte apoptosis.
… confirmed these results on muscle mass and function in response to the treatment of DHEA. …