Factors contributing to muscle wasting and dysfunction in COPD patients

RCI Wüst, H Degens - International journal of chronic obstructive …, 2007 - Taylor & Francis
… Here we only briefly discuss several of the more common potential treatments that target
skeletal muscle wasting during COPD. For a more extensive discussion we refer the reader to …

Muscle wasting in heart failure: an overview

S von Haehling, L Steinbeck, W Doehner… - The international journal …, 2013 - Elsevier
… and possible treatment approaches to muscle wasting in … muscle wasting in health and
disease is paramount in order to develop an understanding of potential therapeutic targets

Peripheral muscle wasting in chronic obstructive pulmonary disease: clinical relevance and mechanisms

R Debigare, CH Cote, F Maltais - American journal of respiratory …, 2001 - atsjournals.org
… Effective treatment for muscle wasting has yet to be developed, but there is now evidence, …
Thus, improving peripheral muscle function could be a reasonable therapeutic target in …

[HTML][HTML] IKKβ/NF-κB activation causes severe muscle wasting in mice

D Cai, JD Frantz, NE Tawa, PA Melendez, BC Oh… - Cell, 2004 - cell.com
… Denervation- and tumor-induced muscle loss were substantially reduced and survival rates
muscle wasting and establishing it as an important clinical target for the treatment of muscle

Elevated expression of activins promotes muscle wasting and cachexia

JL Chen, KL Walton, CE Winbanks… - The FASEB …, 2014 - Wiley Online Library
… in treated limbs induced severe local muscle wasting and led to … to identify activin target
genes in mouse skeletal muscle. … of muscles undergoing hypertrophy after treatment with soluble …

Post burn muscle wasting and the effects of treatments

C Pereira, K Murphy, M Jeschke… - The international journal of …, 2005 - Elsevier
… catabolic effects leading to muscle wasting, the intensity of … of burn wound, aggressive
treatment of sepsis, elevation of the … of post-burn muscle proteolysis and the effects of clinical and …

Mechanism and novel therapeutic approaches to wasting in chronic disease

N Ebner, J Springer, K Kalantar-Zadeh, M Lainscak… - Maturitas, 2013 - Elsevier
Muscle wasting is encountered in virtually all chronic disease … We discuss therapeutic
targets and such potential … is pivotal for the prompt recognition and effective treatment of CKD …

Cancer-associated muscle wasting—candidate mechanisms and molecular pathways

VS Armstrong, LW Fitzgerald, OF Bathe - International Journal of …, 2020 - mdpi.com
… mechanisms for inducing muscle wasting will be reviewed. Potential targets for future …
to explore potential strategies that could be used to treat cancer-associated muscle wasting. …

Promising treatments for muscle wasting in cancer: focus on microRNA

M Beltrà, P Costelli, F Penna - Expert Review of Quality of Life in …, 2016 - Taylor & Francis
… represent the targets of … muscle wasting in cancer and the available treatments are
discussed. Afterwards, a particular attention is given to recently discovered new potential targets, …

Selective androgen receptor modulators (SARMs) as pharmacological treatment for muscle wasting in ongoing clinical trials

GWPD Fonseca, E Dworatzek, N Ebner… - Expert opinion on …, 2020 - Taylor & Francis
… Indeed, considering the limitations to be addressed in future studies and the treatment
potential of drug-related muscle wasting, we may see some of these compounds advancing into …