Inflammation and skeletal muscle wasting during cachexia

JM Webster, LJAP Kempen, RS Hardy… - Frontiers in …, 2020 - frontiersin.org
… and adipose tissue that strongly affects mortality and treatment efficacy in patients with … of
muscle wasting, through the inhibition of muscle protein synthesis (MPS), activation of muscle

Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6

JE Belizário, CC Fontes-Oliveira, JP Borges… - Springerplus, 2016 - Springer
… process and skeletal muscle regeneration during different … production promote skeletal
muscle wasting. These distinct … -6R for the treatment of skeletal muscle wasting and cachexia. …

Muscle wasting in chronic kidney disease: mechanism and clinical implications—a narrative review

TC Cheng, SH Huang, CL Kao, PC Hsu - International Journal of …, 2022 - mdpi.com
… Emerging therapeutic strategies have been proposed to target muscle wasting in patients with
Treatments targeting the mineral and bone disorders developed in CKD through vitamin D …

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

RCJ Langen, HR Gosker, AHV Remels… - The international journal …, 2013 - Elsevier
… triggers of muscle wasting in COPD. … muscle wasting in COPD, as well as the data derived
from experimental models supporting a causal contribution of these factors to muscle wasting

[HTML][HTML] Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia

DT Hall, JF Ma, S Di Marco, IE Gallouzi - Aging (Albany NY), 2011 - ncbi.nlm.nih.gov
muscle wasting and as a therapeutic target for the treatment of both sarcopenia and cachexia.
Although recent attempts to target … represent better targets to combat muscle wasting. One …

Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia

BT Steffen, SJ Lees, FW Booth - Journal of applied …, 2008 - journals.physiology.org
… in EDL wasting, by improving appetite in sTNFR1-treated, ad … , simultaneous treatments,
which not only target inflammatory … anorexia, to counter muscle wasting from cardiac cachexia. …

Recent progress in elucidating signalling proteolytic pathways in muscle wasting: potential clinical implications

C Polge, AE Heng, L Combaret, D Béchet… - Nutrition, Metabolism …, 2013 - Elsevier
muscle fibre size and strength upon catabolic treatment. … to elucidate signalling pathways of
muscle wasting that are much more … of muscle mass should be more efficient if we can target

Control of ubiquitination in skeletal muscle wasting

SS Wing - The international journal of biochemistry & cell biology, 2005 - Elsevier
targets in the search for therapies for wasting disorders. In this article, the enzymes that
can modulate ubiquitination are briefly reviewed and the current data regarding regulation of …

Muscle wasting: A review of exercise, classical and non‐classical RAS axes

MA Winslow, SE Hall - Journal of Cellular and Molecular …, 2019 - Wiley Online Library
… in proper treatment, which is why many treatmentstarget for SIRT1 as well as NF-κB and
myogenic differentiation antigen (MyoD), which are linked to proteolysis and muscle wasting.46 …

Exercise-induced myokines with therapeutic potential for muscle wasting

R Piccirillo - Frontiers in physiology, 2019 - frontiersin.org
… Their protective lipid bilayers could facilitate them to target muscle-unrelated tissues,
affecting overall body homeostasis. This would further help explain how genetic modifications …