Skeletal muscle wasting in chronic kidney disease: the emerging role of microRNAs

KA Robinson, LA Baker… - Nephrology Dialysis …, 2020 - academic.oup.com
… In CKD, expression of miRNA-486 (targets FoxO1 and PTEN), miRNA-26a (targets FoxO1 …
-based therapeutics for the treatment of muscle wasting in CKD and other catabolic conditions. …

Role of β-adrenoceptor signaling in skeletal muscle: implications for muscle wasting and disease

GS Lynch, JG Ryall - Physiological reviews, 2008 - journals.physiology.org
muscle is important for identifying new therapeutic targets and identifying novel approaches
to attenuate the muscle wasting … that treatment with either compound increased muscle

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

K Lenk, G Schuler, V Adams - Journal of cachexia, sarcopenia and muscle, 2010 - Springer
… So far, not many treatment options to fight the muscle loss … in the skeletal muscle of both
muscle wasting disorders. In … ) is a selective target associated with a wasting state compared to …

Inhibitors of myostatin-and proteasome-dependent signaling for attenuating muscle wasting

K Sakuma, A Yamaguchi - Recent Patents on Regenerative …, 2011 - ingentaconnect.com
… Although the treatment of muscle wasting due to starvation … The ubiquitin-proteasome
pathway as a therapeutic target for muscle wasting. J Support Oncol 2005; 3: 209-17. [144] Kwak …

[HTML][HTML] Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival

X Zhou, JL Wang, J Lu, Y Song, KS Kwak, Q Jiao… - Cell, 2010 - cell.com
… potential for treating various types of muscle wasting, especially cancer cachexia. … To
examine whether ActRIIB pathway blockade is also effective in reversing muscle wasting induced …

Epigenetic drugs in the treatment of skeletal muscle atrophy

V Guasconi, PL Puri - Current Opinion in Clinical Nutrition & …, 2008 - journals.lww.com
… of muscle atrophy have revealed potential targets for … with muscle wasting and cachexia
[46] . Consequently, genetic interference of the NFkB signaling attenuates muscle wasting [47] . …

Metabolic remodeling in skeletal muscle atrophy as a therapeutic target

A Renzini, CS Riera, I Minic, C D'Ercole… - Metabolites, 2021 - mdpi.com
… We will discuss how physical exercise or nutritional support can counteract muscle wasting,
… myoblasts [217], thus supporting the use of vitamin D to treat muscle wasting in cachexia. …

[PDF][PDF] Muscle wasting and IL-6

T Tsujinaka, C Ebisui, J Fujita, M Kishibuchi, M Yano… - BAM-PADOVA-, 1998 - bio.unipd.it
… cancer cachexia and muscle wasting, though … treatment with a specific antibody in vivo and
in vitro, and (4) the level in circulation increases in clinical situations inducing muscle wasting

The impact of senescence on muscle wasting in chronic kidney disease

Y Huang, B Wang, F Hassounah… - … and muscle, 2023 - Wiley Online Library
… ameliorated muscle wasting and improved muscle strength in vivo … targets to improve muscle
health and function in CKD. … and TA muscles over the same muscles of vehicle-treated CKD …

Oxidative stress, chronic disease, and muscle wasting

JS Moylan, MB Reid - Muscle & Nerve: Official Journal of the …, 2007 - Wiley Online Library
… Diagram shows targets of interventions to alleviate catabolic processes of … An interesting
approach yet to be tested for treatment of muscle wasting was recently shown to be effective in …