Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir

K Kalantar, AG Talepoor, ME Vakili, N Karami, M Kalani… - Immunobiology, 2023 - Elsevier
… = 29) before, and after treatment with Remdesivir as well as in … (before treatment) and 5 days
after treatment with Remdesivir. … 5 days after Remdesivir treatment. Comparing with before …

Remdesivir for the treatment of Covid-19

…, S Pett, JD Neaton, TH Burgess… - … England Journal of …, 2020 - Mass Medical Soc
… In addition, in nonhuman primate studies, remdesivir initiated 12 hours after inoculation with
… -19 Treatment Trial (ACTT-1), in which we evaluated treatment with remdesivir as compared …

Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis

A Rezagholizadeh, S Khiali, P Sarbakhsh… - European journal of …, 2021 - Elsevier
… of remdesivir as the first officially approved agent for COVID-19 treatment, we performed
this systematic review and meta-analysis to evaluate the efficacy and safety of remdesivir

Remdesivir for the treatment of Covid-19—preliminary report

…, S Pett, JD Neaton, TH Burgess… - … England Journal of …, 2020 - discovery.ucl.ac.uk
… Our data also suggest that treatment with remdesivir may … failure among patients in the
remdesivir group, as well as a lower … Treatment with remdesivir was associated with fewer days of …

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice

A Schäfer, DR Martinez, JJ Won, RM Meganck… - Science Translational …, 2022 - science.org
treated groups (P = 0.0001 and P < 0.0001, respectively; Fig. 2C). To monitor the effect of drug
treatment … of mice from each group (N = 4 per treatment group). The WBP metric PenH is a …

[HTML][HTML] Clinical experience with use of remdesivir in the treatment of severe acute respiratory syndrome coronavirus 2: a case series

…, JP Choi, C Hahm, H Kim, S Kim, TH Kim… - Infection & …, 2020 - ncbi.nlm.nih.gov
Remdesivir (RDV), a monophosphoramidate prodrug of a C-adenosine nucleoside analogue,
is expected to be a particularly effective treatment for … of treating COVID-19 with RDV. …

[HTML][HTML] Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.

A Schäfer, DR Martinez, JJ Won, FR Moreira, AJ Brown… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… To monitor the effect of drug treatment on pulmonary function, we performed daily whole-body
plethysmography (WBP) with a subset of mice from each group (N=4 per …

New perspectives on antimicrobial agents: remdesivir treatment for COVID-19

MM Aleissa, EA Silverman… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… the treatment of hospitalized patients with coronavirus disease 2019 (COVID-19). Remdesivir
is … -19, have demonstrated that early treatment with remdesivir leads to improved survival, …

Remdesivir: critical clinical appraisal for COVID 19 treatment

S Chatterjee - Drug research, 2021 - thieme-connect.com
… the treatment of COVID-19. Based on the evaluation of EUA and clinical evidence available,
considering the non-availability of any drug or treatment options for COVID-19, Remdesivir

A new pharmacological approach based on remdesivir aerosolized administration on SARS-CoV-2 pulmonary inflammation: A possible and rational therapeutic …

C Contini, CE Gallenga, G Neri, M Maritati, P Conti - Medical Hypotheses, 2020 - Elsevier
… RDV appears to have a favorable clinical safety profile, as reported on the basis of experience
in approximately 500 persons, including healthy volunteers and patients treated for acute …