… responses capable of challenging cancer recurrence. This … to cancer vaccination, employing Listeriamonocytogenes vectors, … Listeriamonocytogenes (Lm) is a Gram-positive bacteria …
LM Wood, Y Paterson - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
… monocytogenes (Lm)-based vaccines. This review will cover the important developments leading up to the application of Lm in tumorimmunotherapy (… for tumorimmunotherapy and the …
LM Wood, PD Guirnalda, MM Seavey, Y Paterson - Immunologic research, 2008 - Springer
… tumorimmunotherapy programs that target breast cancer. In one, we are using Listeria monocytogenes … active form on up to 60% of human breast tumors [44]. Because Her-2/neu is …
R Singh, Y Paterson - Expert review of vaccines, 2006 - Taylor & Francis
… Killing of tumor cells and cross-presentation. (1)Listeriamonocytogenes secreting a tumor … cells, which then present peptides derived from Listeria through MHC I and II molecules. (2) …
P Guirnalda, L Wood, Y Paterson - Advances in Immunology, 2012 - Elsevier
… of Listeriamonocytogenes and its virulence factors as cancer immunotherapeutics. We describe their development as vectors to carry protein tumor … efforts to harness their tumor-homing …
E Theisen, JD Sauer - Inflammasome Signaling and Bacterial Infections, 2016 - Springer
… Listeriamonocytogenes is a Gram-positive intracellular … monocytogenes can activate a robust cell-mediated immune response that is being harnessed as an immunotherapeutic platform…
… with Listeriamonocytogenes vaccines [10]. The possibilities of successful Listeriamonocytogenes cancer … will contribute to innovative anti-cancer therapies that benefit cancer patients. …
M Oladejo, Y Paterson, LM Wood - Frontiers in immunology, 2021 - frontiersin.org
… In this review, we provide a brief background of Listeriamonocytogenes as a vaccine … Listeria-based immunotherapies, and detail the advancements in development of improved Listeria…
SF Hussain, Y Paterson - Cancer Immunology, Immunotherapy, 2005 - Springer
… to successfully treat HPV-associated cancer. Intracellular bacteria are able to generate a … Our lab and those of others have demonstrated the ability of Listeriamonocytogenes to be …