The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
… The first use of cytokine storm to describe the mechanism of an … Although cytokine storm
can be a useful lay term, we must … of the first paper on tumour necrosis factor (TNF),12 allowed …

Clinical “cytokine storm” as revealed by monocyte intracellular flow cytometry: correlation of tumor necrosis factor α with severe gut graft-versus-host disease

DH Fowler, J Foley, JW Hou, J Odom, K Castro… - Clinical …, 2004 - Elsevier
… Using an IC-FCM assay to quantitate posttransplantation monocyte production of IL-1α and
TNF-α, we found that these inflammatory cytokines, which contribute to cytokine storm murine …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… -macrophage colony-stimulating factor (GM-CSF) and interleukin-6 (IL-6). GM-CSF further
… large quantities of IL-6, tumor necrosis factor-α (TNF-α), and other cytokines. Membrane-…

Cytokine storm of acute necrotizing encephalopathy

SM Kansagra, WB Gallentine - Pediatric neurology, 2011 - Elsevier
tumor necrosis factor-α in both the acute and convalescent phases of influenza B-associated
acute necrotizing encephalopathy, but no other cytokine … acute necrotizing encephalopathy …

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been … Cytokine storms (CSs) are associated
with various pathologies, … cytokine release and cell death pathways; certain cytokines, …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… The term ‘cytokine storm syndrome’ is perhaps one of the critical hallmarks of … cytokine
families and their potential role in COVID-19, the type I and II interferons, tumour necrosis factor

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
Tumor necrosis factor (TNF) is perhaps the best known and most intensely … cytokines, and
it plays a prominent role in the cytokine storm literature. The name “tumor necrosis factor” was …

Cytokine drizzle—the rationale for abandoning “cytokine storm

AE Stolarski, J Kim, Q Zhang, DG Remick - Shock, 2021 - journals.lww.com
… , IL-8, IL-10, interferon gamma (IFN-g), interleukin 1 beta (IL-1b), tumor necrosis factor alpha,
and interleukin 1 receptor antagonist (IL-1RA). (Please refer to Supplemental Table 1, https:/…

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… , do trigger life-threatening “cytokine storms” in the host which … candidates for treatment
of cytokine storms which may prove … cytokines and include tumor necrosis factor alpha (TNF-α), …

Dynamics of a cytokine storm

HH Yiu, AL Graham, RF Stengel - 2012 - journals.plos.org
Cytokines … to cytokine production are destabilized, a "cytokine storm" (or hypercytokinemia)
can result, producing unbridled inflammation within tissues and key organs. Cytokine storms