The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… , with markedly higher levels of pro-inflammatory cytokines including interferons (IFNs),
tumor necrosis factors (TNFs), interleukins (ILs), and chemokines, has been detected in patients …

[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… Furthermore, mononuclear macrophages stimulate higher release of proinflammatory cytokines
[ILs and Tumor Necrosis factor (TNF)], thus increasing the severity of the disease. Indeed…

[HTML][HTML] Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice

X Shi, W Zhou, H Huang, H Zhu, P Zhou, H Zhu, D Ju - Critical care, 2013 - Springer
… and mortality include robust cytokine production (cytokine storm), excessive inflammatory …
Tumor necrosis factor-alpha (TNF-α) is an important pro-inflammatory cytokine present during …

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… -inflammatory cytokines such as interleukin (IL)-6, IL-1, tumor necrosis factor (TNF)α, and
IL-8, which in some patients turn out to be a cytokine storm, as discussed more in detail later. …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… -inflammatory cytokines, such as tumor necrosis factor (TNF) … 2, cytokine storm was advocated
as a key pathogenetic factor … numerous inflammatory cytokines, including IL-1β, IL-2, IL-6, …

Cytokine storm and sepsis disease pathogenesis

BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
… Despite the identification of key molecules, such as the emblematic tumor necrosis factor
alpha, every attempt aiming to dampen this cytokine storm activation or consequences failed in …

[PDF][PDF] Cytokine storm

M Gaestel, AR Nebreda, MB Yaffe - 2021 - dspace.mit.edu
… in myeloid and lymphoid cells, including interleukin-6, interleukin-1β, interferon-γ, and
tumor necrosis factor α, through both transcriptional and post-transcriptional mechanisms after …

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
cytokine storms are described from both host and pathogen perspectives. In summary, current
studies indicate that cytokine storm… of various cytokines, such as tumor necrosis factor (TNF…

[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
… of cytokines, particularly tumor necrosis factor (TNF) and interferon gamma (IFN-γ), triggers
inflammatory cell death called PANoptosis and consequently results in cytokine storm [5, 12]. …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
… stimulating factor, IP-10, MCP-1, macrophage inflammatory protein 1A, and tumor necrosis
factor … Overall, Huang et al [26] suggested that the cytokine storm was associated with disease …