… of AP-1-dependent genes is required for tumor promotion … AP-1 transactivation is required
for tumor promotion or tumor … define the role of AP-1 transactivation in tumor promotion and/or …

… protein-1 (AP-1) mediated transcription and cyclooxygenase-2 (COX-2) expression. AP-1
and … increases in AP-1 and COX-2 may play a role in tumor promotion through increases in …

… inhibit phorbol ester tumor promotion and inflam… Jun/AP-1 activity by the glucocorticoid
receptor. Therefore, activation ofc-Jun/AP-1 is probably crucial in transmitting the tumor-promoting …

… The transforming activity of c-Jun and c-Fos suggests that AP-1 … or tumor promotion may
also result from decreased cell death. More direct evidence for the involvement of certain AP-1 …

… Abstract: The transcription factor activator protein 1 (AP-1) plays a … AP-1 activity is increased
in multiple human tumor types. Inhibitors of AP-1 have been shown to block tumor promotion…

… Induction of phase 2 detoxification enzymes by phenolic antioxidants can account for
prevention of tumor initiation but cannot explain why these compounds inhibit tumor promotion. …

… tumor-promoting activity of As3+, we examined its effect on transcription factor AP-1, whose
activity is stimulated by several other tumor … stimulator of AP-1 transcriptional activity and an …

… tumor promoter-induced transformation and AP-1-dependent transactivation [16]. These data
demonstrated that AP-1 is an indispensable mediator of tumor promotion … P− AP-1 defect …

… to implement the process of tumor promotion. The list of such … AP-1 function renders the P-
cell unresponsive to promotion … 3); this similarity suggests that the AP1 protein is present in P…

… Effects of AP-1 on both proliferation and survival are variable and will be discussed
below in the context of tumor promotion or repression. The ability of AP-1 to modulate the …