Mechanistic insights into the role of probiotics in modulating immune cells in ulcerative colitis

N Guo, L Lv - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
Background Ulcerative colitis (UC) is a persistent inflammatory disorder that affects the
gastrointestinal tract, mainly the colon, which is defined by inflammatory responses and the …

Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice: mechanistic insights

P Xia, T Hou, M Ma, S Li, H Jin, X Luo, J Li, F Geng… - Food & Function, 2022 - pubs.rsc.org
ulcerative colitis by skewing macrophage differentiation. However, the mechanism of repairing
the colitis … Therefore, we selected KOS to explore their protective effect on ulcerative colitis

[HTML][HTML] Protective effect and mechanism insight of purified Antarctic krill phospholipids against mice ulcerative colitis combined with bioinformatics

R Huang, J Yao, L Zhou, X Li, J Zhu, Y Hu… - Natural Products and …, 2023 - Springer
… in elucidating its effect mechanism on ulcerative colitis (UC). The mechanism of UC action …
) on dextran sulfate sodium (DSS)-induced colitis mice was verified. GO functional enrichment …

[HTML][HTML] Systems biology approach highlights mechanistic differences between Crohn's disease and ulcerative colitis

PA Ruiz Castro, H Yepiskoposyan, S Gubian… - Scientific Reports, 2021 - nature.com
IBD network models are a valuable tool for scoring high-throughput data to gain molecular
mechanistic insights … -controlled clinical studies, the IBD network model suite can help identify …

Morus macroura Miq. Fruit extract protects against acetic acid-induced ulcerative colitis in rats: Novel mechanistic insights on its impact on miRNA-223 and on the …

RM Salama, SF Darwish, I El Shaffei… - Food and Chemical …, 2022 - Elsevier
ulcerative colitis (UC). Inversely, miRNA-223 can exert counter-regulatory effect on NLRP3
expression. The mulberry tree (Morus macroura) fruit is attaining increased importance for its …

Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight

FEM Ali, MM Elfiky, WA Fadda, HS Ali, AR Mahmoud… - Life Sciences, 2021 - Elsevier
… a novel anti-colitis mechanism of nifuroxazide against the … ulcerative colitis using acetic acid
and received vehicle for 6 days. UC + sulfasalazine group: rats subjected to ulcerative colitis

From genetics of inflammatory bowel disease towards mechanistic insights

DB Graham, RJ Xavier - Trends in immunology, 2013 - cell.com
… As a result, these studies substantially increase the estimated disease heritability for both
Crohn's disease (CD) and ulcerative colitis (UC). Furthermore, they highlight 110 shared loci …

Mechanistic insight: linking cardiovascular complications of inflammatory bowel disease

H Kumarapperuma, R Wang, PJ Little… - Trends in Cardiovascular …, 2023 - Elsevier
… In contrast, ulcerative colitis causes superficial mucosal inflammation limited to the colon, …
There are 163 IBD-associated gene loci; 110 loci are common to both ulcerative colitis and …

The synergistic role of diet and exercise in the prevention, pathogenesis, and management of ulcerative colitis: an underlying metabolic mechanism

J Stavsky, R Maitra - Nutrition and Metabolic Insights, 2019 - journals.sagepub.com
Ulcerative colitis (UC) is a biologically complex condition characterized by chronic, relapsing
inflammation of the gastrointestinal tract. The relative incidence of this debilitating condition …

Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis

RB Sartor - Nature clinical practice Gastroenterology & hepatology, 2006 - nature.com
insights into the pathogenesis of chronic, immune-mediated, intestinal inflammation. These
studies indicate that Crohn's disease and ulcerative colitis … The most convincing mechanistic