Genome-wide association identifies multiple ulcerative colitis susceptibility loci

…, RK Weersma, NIDDK IBD Genetics Consortium… - Nature …, 2010 - nature.com
… Here we focused on five ulcerative colitis susceptibility loci containing genes whose
expression and function are not well established. We performed quantitative real-time PCR in …

Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis

J Umeno, K Asano, T Matsushita… - Inflammatory bowel …, 2011 - academic.oup.com
… 10 susceptibility loci. A comparison of the results of these studies and additional association
studies has identified 18 common susceptibility loci … more ulcerative colitis susceptibility loci

Genetics of ulcerative colitis

AI Thompson, CW Lees - Inflammatory bowel diseases, 2011 - academic.oup.com
… (IBDs), with distinct and overlapping susceptibility loci. Recently, hypothesis-free genome-…
the genetic architecture of IBD. To date, over 60 published IBD susceptibility loci have been …

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Data and Analysis Group: Spencer Chris CA chris … - Nature …, 2009 - nature.com
… We have identified three new susceptibility loci for ulcerative colitis and provide the first
genetic link between ulcerative colitis and colorectal cancer. The strongest new association …

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk

EAM Festen, PCF Stokkers… - Official journal of the …, 2010 - journals.lww.com
susceptibility is known to make a major contribution to the pathogenesis of ulcerative colitis
(UC… studies, including a genome-wide association study (GWAS), reported novel UC risk loci. …

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

K Asano, T Matsushita, J Umeno, N Hosono… - Nature …, 2009 - nature.com
ulcerative colitis susceptibility. In summary, our GWAS identified three new ulcerative colitis
susceptibility loci … Our findings should shed light on the pathogenesis of ulcerative colitis and …

Identification of ten additional susceptibility loci for ulcerative colitis through immunochip analysis in Koreans

BD Ye, H Choi, M Hong, WJ Yun… - Inflammatory bowel …, 2016 - academic.oup.com
… reported 3 loci associated with Korean ulcerative colitis (UC). … to identify new UC associations
with loci implicated in other … Immunochip analysis for susceptibility loci of UC in Koreans. …

Genetic susceptibility in IBD: overlap between ulcerative colitis and Crohn's disease

JD Doecke, LA Simms, ZZ Zhao… - Inflammatory bowel …, 2013 - academic.oup.com
… test whether recently identified CD loci 7 additionally confer susceptibility to both CD and UC…
susceptibility locus, and suggested four other possible shared UC-CD susceptibility loci that …

Mapping of a disease susceptibility locus in chromosome 6p in Japanese patients with ulcerative colitis

E Nomura, Y Kinouchi, K Negoro, Y Kojima… - Genes & …, 2004 - nature.com
Ulcerative colitis (UC) is a multifactorial disorder with both genetic and environmental …
susceptible gene has not been identified yet. In this study, to map precisely the susceptible locus

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

CA Anderson, DCO Massey, JC Barrett, NJ Prescott… - Gastroenterology, 2009 - Elsevier
… Through follow-up of discoveries from the recent CD meta-analysis, this study identifies 4
new susceptibility loci for UC. In addition, we provide replicated association and thereby …