… the onset of kidney development. To determine roles of FGFR1 and FGFR2 in the ureteric
bud, we … and green fluorescent protein expression throughout ureteric bud tissue. We crossed …

… ureteric bud (UB) organoid culture model that can be derived from primary UB progenitors
from mouse and human fetal kidneys… for recapitulating kidney development and disease using …

… Kidneys develop from a subregion of the embryonic mesodermal tissue, the intermediate
mesoderm that generates two key cell types, the epithelial—ureteric bud (UB), and the …

… Much of the classical work in the developing kidney has focused on the signals and the
consequences of induction, as defined by the contact of the ureteric bud epithelium with the …

… To address this possibility in the UB, we first utilized a cell line derived from the ureteric bud
(UB cells). These cells have been shown to secrete several factors that can induce nephron …

… ureteric bud originates from the posteromedial aspect of the mesonephric duct at the point
where it enters the cloaca. The ureteric bud, … the upper and lower poles develop faster than the …

… Branching morphogenesis of the ureteric bud is important in mammalian kidney development.
A great deal is now known about which signaling pathways and transcription factors …

… kidney development starts when an epithelial tubule called the ureteric bud invades a
mass … The ureteric bud “induces” mesenchymal cells to proliferate and convert to epithelia. …

… kidney development, the highly proliferative ureteric bud (UB) epithelial cells undergo
branching morphogenesis and differentiate to form a functional collecting duct tree of the kidney. …

… Three-dimensional rendering of the branched ureteric bud of a mouse kidney at embryonic
… METANEPHRIC KIDNEY Metanephric kidney development initiates when the ureteric bud (…