[HTML][HTML] Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem …

J Tay, A Tinmouth, D Fergusson, L Huebsch… - Biology of Blood and …, 2007 - Elsevier
… Point estimate of relative risk of hepatic veno-occlusive disease (HVOD) and 95% confidence
interval in the 3 randomized trials comparing ursodeoxycholic acid with no treatment as …

The Japanese multicenter open randomized trial of ursodeoxycholic acid prophylaxis for hepatic venoocclusive disease after stem cell transplantation

K Ohashi, J Tanabe, R Watanabe… - American journal of …, 2000 - Wiley Online Library
… Hepatic venoocclusive disease (VOD) is a common transplant‐related complication of …
Limited studies have suggested that prophylactic use of ursodeoxycholic acid (UDCA) reduced …

[HTML][HTML] Veno occlusive disease: update on clinical management

M Senzolo, G Germani, E Cholongitas… - World journal of …, 2007 - ncbi.nlm.nih.gov
… Prophylactic administration of ursodeoxycholic acid, being an antioxidant and antiapoptotic
agent, can have some benefit in reducing overall mortality. Defibrotide, which has pro-…

Veno-occlusive disease of the liver

SI Bearman - Current Opinion in Oncology, 2000 - journals.lww.com
… [30•] conducted a randomized study of ursodiol in … ursodiol should prevent VOD is unclear.
It is postulated that the replacement of toxic hydrophobic bile acids with hydrophilic ursodiol

Ursodeoxycholic acid therapy in hepatobiliary disease

KV Kowdley - The American journal of medicine, 2000 - Elsevier
Veno-occlusive disease A recent study suggests that ursodeoxycholic acid treatment might
prevent hepatic veno-occlusive disease after bone marrow transplantation (46). This dreaded …

[HTML][HTML] Hepatic veno-occlusive disease after hematopoietic stem cell transplantation: Prophylaxis and treatment controversies

DKL Cheuk - World journal of transplantation, 2012 - ncbi.nlm.nih.gov
ursodeoxycholic acid with no ursodeoxycholic acid[27]. Two of 71 patients (2.8%) in the
ursodeoxycholic acid … trial again compared ursodeoxycholic acid with no ursodeoxycholic acid[28…

A randomized trial of heparin plus ursodiol vs heparin alone to prevent hepatic veno-occlusive disease after hematopoietic stem cell transplantation

SH Park, MH Lee, H Lee, HS Kim, K Kim… - Bone marrow …, 2002 - nature.com
Ursodiol (ursodeoxycholic acid; UDCA) is a naturally occurring hydrophilic bile salt that
has shown efficacy in the treatment of some hepatic disorders. Recently, prophylactic use …

Prevention and treatment of veno-occlusive disease

AA Pegram, LAD Kennedy - Annals of Pharmacotherapy, 2001 - journals.sagepub.com
… E1, ursodiol, and glutamine have been studied for prevention of veno-occlusive disease. …
been clearly established in patients with veno-occlusive disease. Other possible treatment …

Late onset veno-occlusive disease following high-dose chemotherapy and stem cell transplantation

HC Toh, SL McAfee, R Sackstein, BF Cox… - Bone marrow …, 1999 - nature.com
… The original definition of hepatic veno-occlusive disease (VOD), … Ursodeoxycholic acid was
used as VOD prophylaxis … , it is uncertain whether ursodiol or other common characteristics of …

Sinusoidal obstruction syndrome (hepatic veno-occlusive disease)

CQ Fan, JM Crawford - Journal of clinical and experimental hepatology, 2014 - Elsevier
Ursodeoxycholic acid (ursodiol) beginning … ursodeoxycholic acid (ursodiol) reduces the
incidence of SOS in the HSCT population is equivocal.139, 140, 141, 142 Ursodeoxycholic acid