Influenza vaccine responses in older adults

JE McElhaney - Ageing research reviews, 2011 - Elsevier
… programs, call for more effective influenza vaccines in the older population. A greater
understanding of how age-related changes and their interaction with common chronic diseases in …

Immunosenescence and human vaccine immune responses

SN Crooke, IG Ovsyannikova, GA Poland… - Immunity & …, 2019 - Springer
… adults, and we also highlight how studies of adaptive immunosenescence can guide
vaccine research efforts in this population. We also provide an outlook on personalized …

Targeting inflammation and immunosenescence to improve vaccine responses in the elderly

B Pereira, XN Xu, AN Akbar - Frontiers in immunology, 2020 - frontiersin.org
… of adjuvants in influenza vaccination of older populations. Despite this, a … responses to
vaccination in adults ≥ 65 years old randomized to receive one of 4 seasonal influenza vaccines

Immune function and vaccine responses in healthy advanced elderly patients

PJ Carson, KL Nichol, J O'Brien, P Hilo… - Archives of internal …, 2000 - jamanetwork.com
OLDEST OLD" persons, those older than 85 years, constitute the most rapidly growing
segment of our population… study 29 of responses to pneumococcal vaccine in elderly persons …

Vaccine effectiveness in older individuals: what has been learned from the influenza-vaccine experience

PO Lang, S Govind, WA Mitchell, CA Siegrist… - Ageing research …, 2011 - Elsevier
… aged population, because: ▶ the accurate assessment of vaccinevaccine response,
methods identifying and measuring it and for understanding its implications for vaccine response

Immunosenescence: implications for response to infection and vaccination in older people

A Pera, C Campos, N López, F Hassouneh, C Alonso… - Maturitas, 2015 - Elsevier
… required to define effective vaccines for older populations. … a real health problem for older
individuals requiring preventive … immune response in order to define effective vaccines against …

Immunological responses to pneumococcal vaccine in frail older people

I Ridda, CR MacIntyre, R Lindley, Z Gao, JS Sullivan… - Vaccine, 2009 - Elsevier
… Pneumococcal vaccines are perceived to offer low protection in … of this vulnerable
population with acceptable responses is … response to pneumococcal vaccines than age alone. …

Vaccine responsiveness in the elderly: best practice for the clinic

R Aspinall, PO Lang - Expert Review of Vaccines, 2014 - Taylor & Francis
… pneumococcal disease in older populations after the introduction of the vaccine. In addition,
they … However, predicting vaccine responses is less accurate in older people compared with …

A systems biology approach to the effect of aging, immunosenescence and vaccine response

GA Poland, IG Ovsyannikova, RB Kennedy… - Current opinion in …, 2014 - Elsevier
population growing in size globally, and the significantly lower adaptive immune responses
generated to vaccines in this population… with respect to vaccine response. We cover how the …

Perspectives on vaccine development for the elderly

E Oviedo-Orta, CKF Li, R Rappuoli - Current Opinion in Immunology, 2013 - Elsevier
… in response to inactivated flavivirus vaccination … In vaccination response to pandemic H1N1
vaccine, the elderly have a minimal increase in antibody affinity whereas younger population