[HTML][HTML] Vaccines and therapies in development for SARS-CoV-2 infections

D Wu, R Koganti, UP Lambe, T Yadavalli… - Journal of clinical …, 2020 - mdpi.com
… for antiviral therapies and vaccines to treat and prevent COVID-19. In this review, we provide
an overview of SARS-CoV-2 and discuss the emerging therapies and vaccines that show …

[HTML][HTML] Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

WS Lee, AK Wheatley, SJ Kent, BJ DeKosky - Nature microbiology, 2020 - nature.com
vaccine studies revealed human clinical safety risks related to ADE, resulting in failed vaccine
… discuss mitigation strategies for SARS-CoV-2 vaccines and therapies in development. We …

[HTML][HTML] SARSCoV-2 immuno-pathogenesis and potential for diverse vaccines and therapies: opportunities and challenges

AR McGill, R Khalil, R Dutta, R Green, M Howell… - Infectious Disease …, 2021 - mdpi.com
… underlying SARS-CoV-2 … therapies, and nucleic acid vaccines showing promise. This
review discusses the advances in the immunopathology of SARS-CoV-2, vaccines and therapies

[HTML][HTML] SARS-CoV-2 escaped natural immunity, raising questions about vaccines and therapies

E Andreano, R Rappuoli - Nature medicine, 2021 - nature.com
… The causative coronavirus SARS-CoV-2 effortlessly spread across the world for almost a year
with only minimal changes to its RNA genome. However, just as … Vaccines and mAbs …

[HTML][HTML] Modeling transmission of SARS-CoV-2 omicron in China

J Cai, X Deng, J Yang, K Sun, H Liu, Z Chen, C Peng… - Nature medicine, 2022 - nature.com
… However, we also estimate that protecting vulnerable individuals by ensuring accessibility
to vaccines and antiviral therapies, and maintaining implementation of nonpharmaceutical …

[HTML][HTML] Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

L Liu, S Iketani, Y Guo, JFW Chan, M Wang, L Liu… - Nature, 2022 - nature.com
… dose of mRNA-based vaccines exhibited substantially … vaccines and therapies, compelling
the development of new interventions that anticipate the evolutionary trajectory of SARS-CoV

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
… Currently, there are no potent effective antiviral therapies available for SARS-CoV-2 [19].
Nonetheless, the United States Food and Drug Administration (US FDA) approvals have sped …

Stopping pandemics before they start: Lessons learned from SARS-CoV-2

AM Edwards, RS Baric, EO Saphire, JB Ulmer - Science, 2022 - science.org
… This Review will describe how each of the vaccines, antibody therapies, and antiviral drugs
that have been approved to date were built on decades of investment in technology and …

[HTML][HTML] SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
… Here we review the mutational landscape on the SARS-CoV-2 structural and non-structural …
and vaccines. We also look at the effectiveness of approved vaccines, antibody therapy and …

[HTML][HTML] COVID-19: unmasking emerging SARS-CoV-2 variants, vaccines and therapeutic strategies

R Raman, KJ Patel, K Ranjan - Biomolecules, 2021 - mdpi.com
vaccines as promising alternatives to conventional vaccine approaches, while the development
of effective antiviral therapies for treating SARS-CoV-… the effect of SARS-CoV-2 infection …