… To understand the distribution of AAV1 in various regions of the primate brain, we targeted
three regions: the striatum, corona radiata, and basal forebrain. The gray matter of the …

… primate brain and spinal cord with AAV5 viral vector after parenchymal delivery. AAV5-CAG-GFP
(1 × 10 13 vector … Our data demonstrate that AAV5 is a very powerful vector for the …

… been performed in the primate brain. In this study, AAV viral vectors of serotypes 1–6 with an
… at comparable titers, and injected in equal amounts into the brains of Chlorocebus sabaeus. …

… There is close correlation between convected GDL and AAV1 vectors within NHP brain. …
the NHP brain parenchyma, as long as one knows the relative affinity of the viral vector serotype …

… ▶We test adeno-associated viruses (AAV) as gene transfer vectors in primate brains. ▶AAV
serotype 8 … We provide neural pathway-selective transgene deliveries using these vectors. …

… about AAV and LV vector tropism in the primate CNS. … vector serotypes differ more in their
transduction efficiency (eg, spread) than in their selectivity for particular neuronal types or brain …

… trafficking of AAV vectors within the primate brain, and consequently … primates have shown
that distribution of AAV vectors is … data with adeno-associated virus serotype 2 (AAV2) in well …

… Transduction of nonhuman primate brain with adeno-associated virus serotype 1: Vector …
Transduction of nonhuman primate brain with adeno-associated virus serotype 1: Vector …

… in rat and non-human primate brain. We screened other AAV serotypes for axonal transport
and … , it is also neuron-specific in rat brain. Our findings show that axonal transport of AAV is …

… This study suggests that both serotypes are capable of targeting neurons that degenerate in
… primate brain and the extent of vector distribution within the brain 4 weeks after transduction …